Bioss

CHRNB Polyclonal Antibody

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

BS-4247R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human CHRNB2.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: acetylcholine receptor beta 2 neural; Acetylcholine receptor beta 4; acetylcholine receptor, nicotinic, beta 2 (neuronal); acetylcholine receptor, nicotinic, beta 4 (neuronal); beta2 human neuronal nicotinic acetylcholine receptor; cholinergic receptor nicotinic beta polypeptide 2; cholinergic receptor, nicotinic beta 2; cholinergic receptor, nicotinic beta 4; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta 4 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 4; cholinergic receptor, nicotinic, beta subunit 2; N-alpha 1; N-alpha 2; Neuronal acetylcholine receptor non-alpha-1 chain; Neuronal acetylcholine receptor non-alpha-2 chain; Neuronal acetylcholine receptor subunit beta-2; Neuronal acetylcholine receptor subunit beta-4; neuronal nicotinic acetylcholine receptor beta 2; neuronal nicotinic receptor beta 4 subunit; nicotinic acetylcholine receptor beta4 subunit

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Gene Aliases: [b]2-nAchR; Acrb-2; Acrb-4; Acrb2; Acrb4; C030030P04Rik; CHRNB2; CHRNB4; EFNL3; nAChRB2

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UniProt ID: (Human) P17787, (Human) P30926, (Rat) P12390, (Mouse) Q9ERK7, (Mouse) Q8R493, (Rat) P12392

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Entrez Gene ID: (Human) 1141, (Human) 1143, (Rat) 54239, (Mouse) 11444, (Mouse) 108015, (Rat) 25103

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Function(s)
acetylcholine-activated cation-selective channel activity protein binding drug binding ligand-gated ion channel activity acetylcholine receptor activity acetylcholine binding protein heterodimerization activity ion channel activity extracellular ligand-gated ion channel activity
Process(es)
action potential conditioned taste aversion response to hypoxia ion transport calcium ion transport smooth muscle contraction signal transduction synaptic transmission, cholinergic neuromuscular synaptic transmission visual perception sensory perception of sound learning memory locomotory behavior associative learning visual learning regulation of dopamine secretion sensory perception of pain vestibulocochlear nerve development optic nerve morphogenesis lateral geniculate nucleus development central nervous system projection neuron axonogenesis positive regulation of B cell proliferation regulation of synaptic transmission, dopaminergic positive regulation of synaptic transmission, dopaminergic positive regulation of dopamine secretion response to nicotine behavioral response to nicotine social behavior regulation of dopamine metabolic process B cell activation response to cocaine regulation of circadian sleep/wake cycle, REM sleep regulation of circadian sleep/wake cycle, non-REM sleep response to ethanol negative regulation of action potential regulation of dendrite morphogenesis neurological system process cognition protein heterooligomerization membrane depolarization regulation of synapse assembly synaptic transmission involved in micturition cation transmembrane transport central nervous system neuron axonogenesis regulation of membrane potential transport regulation of smooth muscle contraction regulation of neurotransmitter secretion positive regulation of transmission of nerve impulse cation transport
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