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Invitrogen
CHRND Polyclonal Antibody
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CHRND Antibody (PA5-87924) in WB
Western blot analysis of CHRND in extracts of various cell lines. Samples were incubated with CHRND Polyclonal antibody (Product # PA5-87924) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-87924
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-245 of human CHRND (NP_0007421)
Conjugate
Form
Liquid
Concentration
1.54 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804508
Product Specific Information
Immunogen sequence: LNEEERLIRH LFQEKGYNKE LRPVAHKEES VDVALALTLS NLISLKEVEE TLTTNVWIEH GWTDNRLKWN AEEFGNISVL RLPPDMVWLP EIVLENNNDG SFQISYSCNV LVYHYGFVYW LPPAIFRSSC PISVTYFPFD WQNCSLKFSS LKYTAKEITL SLKQDAKENR TYPVEWIIID PEGFTENGEW EIVHRPARVN VDPRAPLDSP SRQDITFYLI IRRK; Positive Samples: A-431, 293T, HeLa, Mouse lung; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
Target Information
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetylcholine receptor; Acetylcholine receptor subunit delta; acetylcholine receptor, nicotinic, delta (muscle); AChR delta subunit; cholinergic receptor; cholinergic receptor, nicotinic delta; cholinergic receptor, nicotinic, delta (muscle); cholinergic receptor, nicotinic, delta polypeptide
Gene Aliases: Achr-4; ACHRD; Acrd; CHRND; CMS2A; CMS3A; CMS3B; CMS3C; FCCMS; L10076; SCCMS
UniProt ID: (Human) Q07001, (Mouse) P02716
Entrez Gene ID: (Human) 1144, (Mouse) 11447
skeletal muscle contraction
transport
muscle contraction
signal transduction
synaptic transmission, cholinergic
neuromuscular synaptic transmission
response to nicotine
regulation of membrane potential
skeletal muscle tissue growth
musculoskeletal movement
neuromuscular process
cation transmembrane transport
ion transport
cation transport
ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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