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Proteintech
CIAO1 Polyclonal Antibody
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Product Details
10295-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CIAO1 Fusion Protein Ag0349 (1-223 aa encoded by BC001395)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
10295-1-AP detected 48-55 kDa band because of phosphorylation. 10295-1-AP does well in IHC and IF detection.
Immunogen sequence: MKDSLVLLG RVPAHPDSRC WFLAWNPAGT LLASCGGDRR IRIWGTEGDS WICKSVLSEG HQRTVRKVAW SPCGNYLASA SFDATTCIWK KNQDDFECVT TLEGHENEVK SVAWAPSGNL LATCSRDKSV WVWEVDEEDE YECVSVLNSH TQDVKHVVWH PSQELLASAS YDDTVKLYRE EEDDWVCCAT LEGHESTVWS LAFDPSGQRL ASCSDDRTVR IWRQ (1-223 aa encoded by BC001395)
Target Information
WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CIAO1; cytosolic iron-sulfur protein assembly 1 homolog; Probable cytosolic iron-sulfur protein assembly protein CIAO1; WD repeat domain 39; WD repeat-containing protein 39; WD40 protein Ciao1
Gene Aliases: CIA1; CIAO1; WDR39
UniProt ID: (Human) O76071
Entrez Gene ID: (Human) 9391
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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