Proteintech

CIB1 Polyclonal Antibody

CIB1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CIB1 Antibody (11823-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human breast cancer using 11823-1-AP (CIB1 antibody) at dilution of 1:50 (under 10x lens).

CIB1 Antibody in Immunoprecipitation (IP)

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Product Details

11823-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2400

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Miscellaneous PubMed (MISC)

View 2 publications 2 publications

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CIB1 Fusion Protein Ag2391 (1-191 aa encoded by BC000846)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MGGSGSRLS KELLAEYQDL TFLTKQEILL AHRRFCELLP QEQRSVESSL RAQVPFEQIL SLPELKANPF KERICRVFST SPAKDSLSFE DFLDLLSVFS DTATPDIKSH YAFRIFDFDD DGTLNREDLS RLVNCLTGEG EDTRLSASEM KQLIDNILEE SDIDRDGTIN LSEFQHVISR SPDFASSFKI VL (1-191 aa encoded by BC000846)

Target Information

The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. This protein also interacts with integrin alphabeta, which may implicate this protein as a regulatory molecule for alphabeta.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Identification of calcium and integrin-binding protein 1 as a reprogrammed glucose metabolism mediator to restrict immune cell infiltration in the stromal compartment of pancreatic ductal adenocarcinoma.

Frontiers in immunology

Ma J,Song Y,Zhuang T,Yang H,Yang X,Zheng J,Luo J,Xia Y,Fei X,Chan DW,Wu D,Xu P,Ni P,Dai J,Xu D,Hu Y

Thu May 25 00:00:00 UTC 2023

Frontiers in immunology

Ma J,Song Y,Zhuang T,Yang H,Yang X,Zheng J,Luo J,Xia Y,Fei X,Chan DW,Wu D,Xu P,Ni P,Dai J,Xu D,Hu Y

Thu May 25 00:00:00 UTC 2023

Frontiers in immunology

Ma J,Song Y,Zhuang T,Yang H,Yang X,Zheng J,Luo J,Xia Y,Fei X,Chan DW,Wu D,Xu P,Ni P,Dai J,Xu D,Hu Y

Thu May 25 00:00:00 UTC 2023

Frontiers in immunology

Ma J,Song Y,Zhuang T,Yang H,Yang X,Zheng J,Luo J,Xia Y,Fei X,Chan DW,Wu D,Xu P,Ni P,Dai J,Xu D,Hu Y

Thu May 25 00:00:00 UTC 2023

CHIP-mediated CIB1 ubiquitination regulated epithelial-mesenchymal transition and tumor metastasis in lung adenocarcinoma.

Cell death and differentiation

Liu Y,Zhou Y,Zhang P,Li X,Duan C,Zhang C

Mon Mar 01 00:00:00 UTC 2021

Identification of calcium and integrin-binding protein 1 as a novel regulator of production of amyloid β peptide using CRISPR/Cas9-based screening system.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Chiu YW,Hori Y,Ebinuma I,Sato H,Hara N,Ikeuchi T,Tomita T

Mon Jun 01 00:00:00 UTC 2020

PDI regulates seizure activity via NMDA receptor redox in rats.

Scientific reports

Kim JY,Ko AR,Hyun HW,Min SJ,Kim JE

Wed Feb 15 00:00:00 UTC 2017

PDI regulates seizure activity via NMDA receptor redox in rats.

Scientific reports

Kim JY,Ko AR,Hyun HW,Min SJ,Kim JE

Wed Feb 15 00:00:00 UTC 2017

CIB1 synergizes with EphrinA2 to regulate Kaposi's sarcoma-associated herpesvirus macropinocytic entry in human microvascular dermal endothelial cells.

PLoS pathogens

Bandyopadhyay C,Valiya-Veettil M,Dutta D,Chakraborty S,Chandran B

Sat Feb 01 00:00:00 UTC 2014

CIB1 synergizes with EphrinA2 to regulate Kaposi's sarcoma-associated herpesvirus macropinocytic entry in human microvascular dermal endothelial cells.

PLoS pathogens

Bandyopadhyay C,Valiya-Veettil M,Dutta D,Chakraborty S,Chandran B

Sat Feb 01 00:00:00 UTC 2014

CIB1 synergizes with EphrinA2 to regulate Kaposi's sarcoma-associated herpesvirus macropinocytic entry in human microvascular dermal endothelial cells.

PLoS pathogens

Bandyopadhyay C,Valiya-Veettil M,Dutta D,Chakraborty S,Chandran B

Sat Feb 01 00:00:00 UTC 2014

CIB1 synergizes with EphrinA2 to regulate Kaposi's sarcoma-associated herpesvirus macropinocytic entry in human microvascular dermal endothelial cells.

PLoS pathogens

Bandyopadhyay C,Valiya-Veettil M,Dutta D,Chakraborty S,Chandran B

Sat Feb 01 00:00:00 UTC 2014

p130Cas scaffolds the signalosome to direct adaptor-effector cross talk during Kaposi's sarcoma-associated herpesvirus trafficking in human microvascular dermal endothelial cells.

Journal of virology

Bandyopadhyay C,Veettil MV,Dutta S,Chandran B

Mon Dec 01 00:00:00 UTC 2014

p130Cas scaffolds the signalosome to direct adaptor-effector cross talk during Kaposi's sarcoma-associated herpesvirus trafficking in human microvascular dermal endothelial cells.

Journal of virology

Bandyopadhyay C,Veettil MV,Dutta S,Chandran B

Mon Dec 01 00:00:00 UTC 2014

p130Cas scaffolds the signalosome to direct adaptor-effector cross talk during Kaposi's sarcoma-associated herpesvirus trafficking in human microvascular dermal endothelial cells.

Journal of virology

Bandyopadhyay C,Veettil MV,Dutta S,Chandran B

Mon Dec 01 00:00:00 UTC 2014

p130Cas scaffolds the signalosome to direct adaptor-effector cross talk during Kaposi's sarcoma-associated herpesvirus trafficking in human microvascular dermal endothelial cells.

Journal of virology

Bandyopadhyay C,Veettil MV,Dutta S,Chandran B

Mon Dec 01 00:00:00 UTC 2014

Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington's disease.

Frontiers in molecular neuroscience

Czeredys M,Gruszczynska-Biegala J,Schacht T,Methner A,Kuznicki J

Tue Dec 10 00:00:00 UTC 2013

I. Embryonal vasculature formation recapitulated in transgenic mammary tumor spheroids implanted pseudo-orthotopicly into mouse dorsal skin fold: the organoblasts concept.

F1000Research

Witkiewicz H,Oh P,Schnitzer JE

Mon Mar 17 00:00:00 UTC 2014

I. Embryonal vasculature formation recapitulated in transgenic mammary tumor spheroids implanted pseudo-orthotopicly into mouse dorsal skin fold: the organoblasts concept.

F1000Research

Witkiewicz H,Oh P,Schnitzer JE

Mon Mar 17 00:00:00 UTC 2014

III. Cellular ultrastructures in situ as key to understanding tumor energy metabolism: biological significance of the Warburg effect.

F1000Research

Witkiewicz H,Oh P,Schnitzer JE

Mon Dec 23 00:00:00 UTC 2013

III. Cellular ultrastructures in situ as key to understanding tumor energy metabolism: biological significance of the Warburg effect.

F1000Research

Witkiewicz H,Oh P,Schnitzer JE

Mon Dec 23 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: calcium and integrin binding 1 (calmyrin); calcium and integrin binding, protein kinase interacting protein; Calcium and integrin-binding protein 1; Calcium- and integrin-binding protein; Calmyrin; CIB; CIBP; DNA-dependent protein kinase interacting protein; DNA-PK interaction protein; DNA-PKcs-interacting protein; Kinase-interacting protein; KIP; protein kinase, DNA activated, catalytic polypeptide interacting protein; SIP2-28; SNK-interacting protein 2-28; testicular secretory protein Li 9

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Gene Aliases: CIB; CIB1; Cibkip; CIBP; KIP; KIP1; PRKDCIP; SIP2-28

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UniProt ID: (Human) Q99828, (Rat) Q9R010, (Mouse) Q9Z0F4

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Entrez Gene ID: (Human) 10519, (Rat) 81823, (Mouse) 23991

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Function(s)

calcium ion binding protein binding protein C-terminus binding calcium-dependent protein kinase inhibitor activity Ras GTPase binding protein kinase binding protein serine/threonine kinase inhibitor activity protein anchor ion channel binding metal ion binding

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CIB1 Polyclonal Antibody

CIB1 Antibody (11823-1-AP) in IHC (P)

Product Details

11823-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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