Proteintech

CIB1 Monoclonal Antibody (1D2C12), CoraLite® Plus 488

View all (18) Calmyrin antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

CL488-67901

Applications
Tested Dilution
Publications

Flow Cytometry (Flow)

0.4 µg/1x10^6 cell suspension
-
Product Specifications

Species Reactivity

Bovine, Human, Mouse, Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

1D2C12

Immunogen

Recombinant protein
View immunogen

Conjugate

CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488

Excitation/Emission Max

493/522 nm

Form

Liquid

Purification

Protein A

Storage buffer

PBS with 50% glycerol, 0.5% BSA

Contains

0.05% ProClin 300

Storage conditions

-20°C, store in dark

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: MGGSGSRLSK ELLAEYQDLT FLTKQEILLA HRRFCELLPQ EQRSVESSLR AQVPFEQILS LPELKANPFK ERICRVFSTS PAKDSLSFED FLDLLSVFSD TATPDIKSHY AFRIFDFDDD GTLNREDLSR LVNCLTGEGE DTRLSASEMK QLIDNILEES DIDRDGTINL SEFQHVISRS PDFASSFKIV L

Target Information

The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. This protein also interacts with integrin alphabeta, which may implicate this protein as a regulatory molecule for alphabeta.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: calcium and integrin binding 1 (calmyrin); calcium and integrin binding, protein kinase interacting protein; Calcium and integrin-binding protein 1; Calcium- and integrin-binding protein; Calmyrin; CIB; CIBP; DNA-dependent protein kinase interacting protein; DNA-PK interaction protein; DNA-PKcs-interacting protein; Kinase-interacting protein; KIP; protein kinase, DNA activated, catalytic polypeptide interacting protein; SIP2-28; SNK-interacting protein 2-28; testicular secretory protein Li 9

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Gene Aliases: BOS_20130; CIB; CIB1; Cibkip; CIBP; KIP; KIP1; PRKDCIP; SIP2-28

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UniProt ID: (Bovine) Q17QE5, (Human) Q99828, (Rat) Q9R010, (Mouse) Q9Z0F4

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Entrez Gene ID: (Bovine) 510141, (Human) 10519, (Rat) 81823, (Mouse) 23991

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Function(s)
calcium ion binding protein anchor ion channel binding protein binding protein C-terminus binding calcium-dependent protein kinase inhibitor activity Ras GTPase binding protein kinase binding protein serine/threonine kinase inhibitor activity metal ion binding
Process(es)
apoptotic process cellular response to DNA damage stimulus endomitotic cell cycle negative regulation of cell proliferation positive regulation of calcineurin-NFAT signaling cascade positive regulation of establishment of protein localization to plasma membrane angiogenesis negative regulation of protein phosphorylation positive regulation of protein phosphorylation positive regulation of cell-matrix adhesion response to ischemia double-strand break repair negative regulation of microtubule depolymerization cell adhesion spermatid development positive regulation of cell proliferation negative regulation of neuron projection development platelet formation positive regulation of cell growth positive regulation of cell migration cytoplasmic microtubule organization positive regulation of cell adhesion mediated by integrin thrombopoietin-mediated signaling pathway regulation of cell proliferation negative regulation of apoptotic process positive regulation of catalytic activity negative regulation of megakaryocyte differentiation positive regulation of NF-kappaB transcription factor activity cell division regulation of cell division negative regulation of protein kinase B signaling positive regulation of ERK1 and ERK2 cascade cellular response to tumor necrosis factor cellular response to growth factor stimulus negative regulation of protein serine/threonine kinase activity positive regulation of protein serine/threonine kinase activity positive regulation of cell migration involved in sprouting angiogenesis positive regulation of protein targeting to membrane extrinsic apoptotic signaling pathway positive regulation of substrate adhesion-dependent cell spreading cellular response to nerve growth factor stimulus positive regulation of male germ cell proliferation negative regulation of protein kinase activity cell cycle spermatogenesis cell differentiation
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