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Product Details
H00008483-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2C5
Immunogen
CILP (NP_003604, 129 a.a. approximately 226 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: NCSNYTVRFL CPPGSLRRDT ERIWSPWSPW SKCSAACGQT GVQTRTRICL AEMVSLCSEA SEEGQHCMGQ DCTACDLTCP MGQVNADCDA CMCQDFML
Target Information
Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cartilage intermediate layer protein 1; cartilage intermediate layer protein 1 C1; cartilage intermediate layer protein 1 C2; cartilage intermediate layer protein, nucleotide pyrophosphohydrolase; Cartilage intermediate-layer protein; CILP-1; HGNC:1980
Gene Aliases: CILP; CILP-1; HsT18872; UNQ602/PRO1188
UniProt ID: (Human) O75339
Entrez Gene ID: (Human) 8483
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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