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Proteintech
CIT Polyclonal Antibody
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Product Details
20033-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The antibody recognizes all the isoforms of CIT.
Target Information
This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: citron (rho-interacting, serine/threonine kinase 21); citron kinase; Citron Rho-interacting kinase; citron-K kinase; citron-N; CRIK; CTRO; postsynaptic density protein (citron); Rho-interacting, serine/threonine-protein kinase 21; serine/threonine kinase 21; Serine/threonine-protein kinase 21
Gene Aliases: C030025P15Rik; CIT; Cit-k; CRIK; CRIK-SK; KIAA0949; STK21
UniProt ID: (Human) O14578, (Mouse) P49025, (Rat) E9PSL7
Entrez Gene ID: (Human) 11113, (Mouse) 12704, (Rat) 83620
protein serine/threonine kinase activity
protein binding
ATP binding
SH3 domain binding
PDZ domain binding
metal ion binding
scaffold protein binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Rho GTPase binding
mitotic sister chromatid segregation
G2/M transition of mitotic cell cycle
cytokinesis
protein phosphorylation
Golgi organization
cell cycle
mitotic nuclear division
metaphase/anaphase transition of mitotic cell cycle
multicellular organism development
spermatogenesis
nervous system development
regulation of actin polymerization or depolymerization
phosphorylation
dendrite development
cell differentiation
positive regulation of cytokinesis
intracellular signal transduction
negative regulation of neuron differentiation
generation of neurons
negative regulation of dendrite morphogenesis
cell division
regulation of catalytic activity
regulation of cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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