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CK1 delta Antibody (PA5-109600) in WB
Western blot analysis of CK1 delta in extracts of various cell lines. Samples were incubated with CK1 delta Polyclonal antibody (Product # PA5-109600) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Product Details
PA5-109600
Product Specifications
Species Reactivity
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CSNK1D (NP_620693.1).
Conjugate
Form
Liquid
Concentration
2.28 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855011
Product Specific Information
Immunogen sequence: TYLNFCRSLR FDDKPDYSYL RQLFRNLFHR QGFSYDYVFD WNMLKFGASR AADDAERERR DREERLRHSR NPATRGLPST ASGRLRGTQE VAPPTPLTPT S
Target Information
CSNK1D (CK1 delta), a serine/threonine kinase, plays a critical role in Wnt/beta-catenin signaling pathway. This pathway is important in both development and cancer. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for CK1 delta.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: casein kinase 1; Casein kinase I isoform delta; CK1d; CK1delta; CKI-delta; HGNC:2452; Tau-protein kinase CSNK1D
Gene Aliases: Csnk1d; Hckid
UniProt ID: (Rat) Q06486
Entrez Gene ID: (Rat) 64462
mitotic cell cycle
positive regulation of protein phosphorylation
protein phosphorylation
endocytosis
regulation of cell shape
Wnt signaling pathway
peptidyl-serine phosphorylation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
circadian regulation of gene expression
regulation of circadian rhythm
spindle assembly
positive regulation of canonical Wnt signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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