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Invitrogen
CK1 delta Polyclonal Antibody
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FIGURE: 1 / 4
CK1 delta Antibody (PA5-32129) in ICC/IF
Immunocytochemistry (Confocal immunofluorescence) of CK1 delta in paraformaldehyde-fixed HeLa. Samples were incubated with CK1 delta polyclonal antibody (Product # PA5-32129) using a dilution of 1:500 (green). Alpha-tubulin filaments were labeled with alpha Tubulin monoclonal antibody (Product # MA1-25054) (Red) at 1:2,000.
Product Details
PA5-32129
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Casein Kinase 1 delta. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2549602
Product Specific Information
Recommended positive controls: HeLa, BCL-1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CSNK1D (CK1 delta), a serine/threonine kinase, plays a critical role in Wnt/beta-catenin signaling pathway. This pathway is important in both development and cancer. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for CK1 delta.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: casein kinase 1; casein kinase 1, delta; Casein kinase I isoform delta; CK1d; CK1delta; CKI-delta; CKId; HGNC:2452; Tau-protein kinase CSNK1D
Gene Aliases: 1200006A05Rik; AA409348; ASPS; CKIdelta; CSNK1D; D930010H05Rik; FASPS2; HCKID
UniProt ID: (Human) P48730, (Mouse) Q9DC28
Entrez Gene ID: (Human) 1453, (Mouse) 104318
glycoprotein binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
peptide binding
tau-protein kinase activity
phosphoprotein binding
cadherin binding involved in cell-cell adhesion
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
positive regulation of protein phosphorylation
protein phosphorylation
endocytosis
regulation of cell shape
Wnt signaling pathway
phosphorylation
peptidyl-serine phosphorylation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
circadian regulation of gene expression
regulation of circadian rhythm
rhythmic process
spindle assembly
positive regulation of canonical Wnt signaling pathway
G2/M transition of mitotic cell cycle
DNA repair
rRNA processing
microtubule nucleation
Golgi organization
signal transduction
protein localization to Golgi apparatus
nonmotile primary cilium assembly
COPII vesicle coating
protein localization to cilium
protein localization to centrosome
cell-cell adhesion
cellular response to nerve growth factor stimulus
positive regulation of non-canonical Wnt signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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