Product References
Palmitoylation couples insulin hypersecretion with β cell failure in diabetes.
Cell metabolism
Dong G,Adak S,Spyropoulos G,Zhang Q,Feng C,Yin L,Speck SL,Shyr Z,Morikawa S,Kitamura RA,Kathayat RS,Dickinson BC,Ng XW,Piston DW,Urano F,Remedi MS,Wei X,Semenkovich CF
Tue Feb 07 00:00:00 UTC 2023
Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy.
Nature
Foronda H,Fu Y,Covarrubias-Pinto A,Bocker HT,González A,Seemann E,Franzka P,Bock A,Bhaskara RM,Liebmann L,Hoffmann ME,Katona I,Koch N,Weis J,Kurth I,Gleeson JG,Reggiori F,Hummer G,Kessels MM,Qualmann B,Mari M,Dikić I,Hübner CA
Thu Jun 01 00:00:00 UTC 2023
Coronavirus subverts ER-phagy by hijacking FAM134B and ATL3 into p62 condensates to facilitate viral replication.
Cell reports
Tan X,Cai K,Li J,Yuan Z,Chen R,Xiao H,Xu C,Hu B,Qin Y,Ding B
Tue Apr 25 00:00:00 UTC 2023
Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.
iScience
Miyagi T,Ueda K,Sugimoto M,Yagi T,Ito D,Yamazaki R,Narumi S,Hayamizu Y,Uji-I H,Kuroda M,Kanekura K
Fri Jun 16 00:00:00 UTC 2023
Deficiency of Perry syndrome-associated p150Glued in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities.
NPJ Parkinson's disease
Yu J,Yang X,Zheng J,Sgobio C,Sun L,Cai H
Tue Mar 07 00:00:00 UTC 2023
Deficiency of Perry syndrome-associated p150Glued in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities.
NPJ Parkinson's disease
Yu J,Yang X,Zheng J,Sgobio C,Sun L,Cai H
Tue Mar 07 00:00:00 UTC 2023
A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy.
The Journal of cell biology
Wang X,Jiang X,Li B,Zheng J,Guo J,Gao L,Du M,Weng X,Li L,Chen S,Zhang J,Fang L,Liu T,Wang L,Liu W,Neculai D,Sun Q
Mon May 01 00:00:00 UTC 2023
The mammalian rhomboid protein RHBDL4 protects against endoplasmic reticulum stress by regulating the morphology and distribution of ER sheets.
The Journal of biological chemistry
Lastun VL,Levet C,Freeman M
Wed Jun 01 00:00:00 UTC 2022
The mammalian rhomboid protein RHBDL4 protects against endoplasmic reticulum stress by regulating the morphology and distribution of ER sheets.
The Journal of biological chemistry
Lastun VL,Levet C,Freeman M
Wed Jun 01 00:00:00 UTC 2022
The mammalian rhomboid protein RHBDL4 protects against endoplasmic reticulum stress by regulating the morphology and distribution of ER sheets.
The Journal of biological chemistry
Lastun VL,Levet C,Freeman M
Wed Jun 01 00:00:00 UTC 2022
The mammalian rhomboid protein RHBDL4 protects against endoplasmic reticulum stress by regulating the morphology and distribution of ER sheets.
The Journal of biological chemistry
Lastun VL,Levet C,Freeman M
Wed Jun 01 00:00:00 UTC 2022
Proteomic Mapping and Targeting of Mitotic Pericentriolar Material in Tumors Bearing Centrosome Amplification.
Cancer research
Xie B,Pu Y,Yang F,Chen W,Yue W,Ma J,Zhang N,Jiang Y,Wu J,Lin Y,Liang X,Wang C,Zou P,Li M
Mon Jul 18 00:00:00 UTC 2022
Targeting FAM134B-mediated reticulophagy activates sorafenib-induced ferroptosis in hepatocellular carcinoma.
Biochemical and biophysical research communications
Liu Z,Ma C,Wang Q,Yang H,Lu Z,Bi T,Xu Z,Li T,Zhang L,Zhang Y,Liu J,Wei X,Li J
Sat Jan 22 00:00:00 UTC 2022
Malondialdehyde-Acetaldehyde Extracellular Matrix Protein Adducts Attenuate Unfolded Protein Response During Alcohol and Smoking-Induced Pancreatitis.
Gastroenterology
Bhatia R,Thompson CM,Clement EJ,Ganguly K,Cox JL,Rauth S,Siddiqui JA,Mashiana SS,Jain M,Wyatt TA,Mashiana HS,Singh S,Woods NT,Kharbanda KK,Batra SK,Kumar S
Sat Oct 01 00:00:00 UTC 2022
ATF4 links ER stress with reticulophagy in glioblastoma cells.
Autophagy
Zielke S,Kardo S,Zein L,Mari M,Covarrubias-Pinto A,Kinzler MN,Meyer N,Stolz A,Fulda S,Reggiori F,Kögel D,van Wijk S
Wed Sep 01 00:00:00 UTC 2021
ATF4 links ER stress with reticulophagy in glioblastoma cells.
Autophagy
Zielke S,Kardo S,Zein L,Mari M,Covarrubias-Pinto A,Kinzler MN,Meyer N,Stolz A,Fulda S,Reggiori F,Kögel D,van Wijk S
Wed Sep 01 00:00:00 UTC 2021
RNA-Binding Profiles of CKAP4 as an RNA-Binding Protein in Myocardial Tissues.
Frontiers in cardiovascular medicine
Zhu H,Zhang Y,Zhang C,Xie Z
Tue Jan 11 00:00:00 UTC 2022
RNA-Binding Profiles of CKAP4 as an RNA-Binding Protein in Myocardial Tissues.
Frontiers in cardiovascular medicine
Zhu H,Zhang Y,Zhang C,Xie Z
Tue Jan 11 00:00:00 UTC 2022
N-glycan processing selects ERAD-resistant misfolded proteins for ER-to-lysosome-associated degradation.
The EMBO journal
Fregno I,Fasana E,Soldà T,Galli C,Molinari M
Mon Aug 02 00:00:00 UTC 2021
MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B.
The EMBO journal
Cinque L,De Leonibus C,Iavazzo M,Krahmer N,Intartaglia D,Salierno FG,De Cegli R,Di Malta C,Svelto M,Lanzara C,Maddaluno M,Wanderlingh LG,Huebner AK,Cesana M,Bonn F,Polishchuk E,Hübner CA,Conte I,Dikic I,Mann M,Ballabio A,Sacco F,Grumati P,Settembre C
Tue Sep 01 00:00:00 UTC 2020
BPIFB3 Regulates Endoplasmic Reticulum Morphology To Facilitate Flavivirus Replication.
Journal of virology
Evans AS,Lennemann NJ,Coyne CB
Thu Apr 16 00:00:00 UTC 2020
Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex.
Molecular cell
van de Weijer ML,Krshnan L,Liberatori S,Guerrero EN,Robson-Tull J,Hahn L,Lebbink RJ,Wiertz EJHJ,Fischer R,Ebner D,Carvalho P
Thu Oct 15 00:00:00 UTC 2020
Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex.
Molecular cell
van de Weijer ML,Krshnan L,Liberatori S,Guerrero EN,Robson-Tull J,Hahn L,Lebbink RJ,Wiertz EJHJ,Fischer R,Ebner D,Carvalho P
Thu Sep 03 00:00:00 UTC 2020
CALCOCO1 acts with VAMP-associated proteins to mediate ER-phagy.
The EMBO journal
Nthiga TM,Kumar Shrestha B,Sjøttem E,Bruun JA,Bowitz Larsen K,Bhujabal Z,Lamark T,Johansen T
Mon Aug 03 00:00:00 UTC 2020
Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum.
The Journal of cell biology
Guadagno NA,Margiotta A,Bjørnestad SA,Haugen LH,Kjos I,Xu X,Hu X,Bakke O,Margadant F,Progida C
Mon Jul 06 00:00:00 UTC 2020
The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.
Cell death & disease
Gao L,Wang Q,Ren W,Zheng J,Li S,Dou Z,Kong X,Liang X,Zhi K
Thu Jun 25 00:00:00 UTC 2020
The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.
Cell death & disease
Gao L,Wang Q,Ren W,Zheng J,Li S,Dou Z,Kong X,Liang X,Zhi K
Thu Jun 25 00:00:00 UTC 2020
Proteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation.
Scientific reports
Yamanaka T,Nishiyama R,Shimogori T,Nukina N
Wed May 06 00:00:00 UTC 2020
Proteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation.
Scientific reports
Yamanaka T,Nishiyama R,Shimogori T,Nukina N
Wed May 06 00:00:00 UTC 2020
SENCR stabilizes vascular endothelial cell adherens junctions through interaction with CKAP4.
Proceedings of the National Academy of Sciences of the United States of America
Lyu Q,Xu S,Lyu Y,Choi M,Christie CK,Slivano OJ,Rahman A,Jin ZG,Long X,Xu Y,Miano JM
Tue Jan 08 00:00:00 UTC 2019
SENCR stabilizes vascular endothelial cell adherens junctions through interaction with CKAP4.
Proceedings of the National Academy of Sciences of the United States of America
Lyu Q,Xu S,Lyu Y,Choi M,Christie CK,Slivano OJ,Rahman A,Jin ZG,Long X,Xu Y,Miano JM
Tue Jan 08 00:00:00 UTC 2019
Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion.
Journal of proteome research
Cao Y,Ding W,Zhang J,Gao Q,Yang H,Cao W,Wang Z,Fang L,Du R
Fri May 03 00:00:00 UTC 2019
Excessive ER-phagy mediated by the autophagy receptor FAM134B results in ER stress, the unfolded protein response, and cell death in HeLa cells.
The Journal of biological chemistry
Liao Y,Duan B,Zhang Y,Zhang X,Xia B
Fri Dec 27 00:00:00 UTC 2019
ER-to-lysosome-associated degradation of proteasome-resistant ATZ polymers occurs via receptor-mediated vesicular transport.
The EMBO journal
Fregno I,Fasana E,Bergmann TJ,Raimondi A,Loi M,Soldà T,Galli C,D'Antuono R,Morone D,Danieli A,Paganetti P,van Anken E,Molinari M
Mon Sep 03 00:00:00 UTC 2018
ER-to-lysosome-associated degradation of proteasome-resistant ATZ polymers occurs via receptor-mediated vesicular transport.
The EMBO journal
Fregno I,Fasana E,Bergmann TJ,Raimondi A,Loi M,Soldà T,Galli C,D'Antuono R,Morone D,Danieli A,Paganetti P,van Anken E,Molinari M
Mon Sep 03 00:00:00 UTC 2018
MicroRNA-671-3p promotes proliferation and migration of glioma cells via targeting CKAP4.
OncoTargets and therapy
Lu GF,You CY,Chen YS,Jiang H,Zheng X,Tang WW,Wang XY,Xu HY,Geng F
Mon Mar 21 00:00:00 UTC 2022
MicroRNA-671-3p promotes proliferation and migration of glioma cells via targeting CKAP4.
OncoTargets and therapy
Lu GF,You CY,Chen YS,Jiang H,Zheng X,Tang WW,Wang XY,Xu HY,Geng F
Mon Mar 21 00:00:00 UTC 2022
MicroRNA-671-3p promotes proliferation and migration of glioma cells via targeting CKAP4.
OncoTargets and therapy
Lu GF,You CY,Chen YS,Jiang H,Zheng X,Tang WW,Wang XY,Xu HY,Geng F
Mon Mar 21 00:00:00 UTC 2022
MicroRNA-671-3p promotes proliferation and migration of glioma cells via targeting CKAP4.
OncoTargets and therapy
Lu GF,You CY,Chen YS,Jiang H,Zheng X,Tang WW,Wang XY,Xu HY,Geng F
Mon Mar 21 00:00:00 UTC 2022
Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B.
Autophagy
Lennemann NJ,Coyne CB
Wed Feb 01 00:00:00 UTC 2017
Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B.
Autophagy
Lennemann NJ,Coyne CB
Wed Feb 01 00:00:00 UTC 2017
Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy.
eLife
Grumati P,Morozzi G,Hölper S,Mari M,Harwardt MI,Yan R,Müller S,Reggiori F,Heilemann M,Dikic I
Thu Jun 15 00:00:00 UTC 2017
Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy.
eLife
Grumati P,Morozzi G,Hölper S,Mari M,Harwardt MI,Yan R,Müller S,Reggiori F,Heilemann M,Dikic I
Thu Jun 15 00:00:00 UTC 2017
Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy.
eLife
Grumati P,Morozzi G,Hölper S,Mari M,Harwardt MI,Yan R,Müller S,Reggiori F,Heilemann M,Dikic I
Thu Jun 15 00:00:00 UTC 2017
Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy.
eLife
Grumati P,Morozzi G,Hölper S,Mari M,Harwardt MI,Yan R,Müller S,Reggiori F,Heilemann M,Dikic I
Thu Jun 15 00:00:00 UTC 2017
Sequestosome 1/p62 Protein Is Associated with Autophagic Removal of Excess Hepatic Endoplasmic Reticulum in Mice.
The Journal of biological chemistry
Yang H,Ni HM,Guo F,Ding Y,Shi YH,Lahiri P,Fröhlich LF,Rülicke T,Smole C,Schmidt VC,Zatloukal K,Cui Y,Komatsu M,Fan J,Ding WX
Fri Sep 02 00:00:00 UTC 2016
Sequestosome 1/p62 Protein Is Associated with Autophagic Removal of Excess Hepatic Endoplasmic Reticulum in Mice.
The Journal of biological chemistry
Yang H,Ni HM,Guo F,Ding Y,Shi YH,Lahiri P,Fröhlich LF,Rülicke T,Smole C,Schmidt VC,Zatloukal K,Cui Y,Komatsu M,Fan J,Ding WX
Fri Sep 02 00:00:00 UTC 2016
Regulation of endoplasmic reticulum turnover by selective autophagy.
Nature
Khaminets A,Heinrich T,Mari M,Grumati P,Huebner AK,Akutsu M,Liebmann L,Stolz A,Nietzsche S,Koch N,Mauthe M,Katona I,Qualmann B,Weis J,Reggiori F,Kurth I,Hübner CA,Dikic I
Thu Jun 18 00:00:00 UTC 2015
Regulation of endoplasmic reticulum turnover by selective autophagy.
Nature
Khaminets A,Heinrich T,Mari M,Grumati P,Huebner AK,Akutsu M,Liebmann L,Stolz A,Nietzsche S,Koch N,Mauthe M,Katona I,Qualmann B,Weis J,Reggiori F,Kurth I,Hübner CA,Dikic I
Thu Jun 18 00:00:00 UTC 2015
The endogenous caspase-8 inhibitor c-FLIPL regulates ER morphology and crosstalk with mitochondria.
Cell death and differentiation
Marini ES,Giampietri C,Petrungaro S,Conti S,Filippini A,Scorrano L,Ziparo E
Wed Jul 01 00:00:00 UTC 2015
The endogenous caspase-8 inhibitor c-FLIPL regulates ER morphology and crosstalk with mitochondria.
Cell death and differentiation
Marini ES,Giampietri C,Petrungaro S,Conti S,Filippini A,Scorrano L,Ziparo E
Wed Jul 01 00:00:00 UTC 2015
