Invitrogen

CKS2 Monoclonal Antibody (1F7G5)

3 Published Figures

10 References

View all (12) CKS2 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (1)
Published Figures (3)

FIGURE: 1 / 4

CKS2 Antibody (37-0300) in WB

Western blot analysis of recombinant Cks2 using Ms anti-Cks2 (Product # 37-0300).

CKS2 Antibody in Immunocytochemistry (ICC/IF)

CKS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

CKS2 Antibody in Immunohistochemistry, Immunohistochemistry (Frozen) (IHC, IHC (F))

Product Image Gallery

Product Details

37-0300

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

ELISA (ELISA)

Assay-dependent

Immunoprecipitation (IP)

Assay-dependent

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse, Tag

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1F7G5

Immunogen

A synthetic peptide derived from the C-terminal region of human CKS2.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.1% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2533291

Target Information

CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS2 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects specialized role for the encoded protein. [provided by RefSeq, Jul 2008]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Single cell transcriptomics reveals the heterogeneity of the human cornea to identify novel markers of the limbus and stroma.

Scientific reports

Català P,Groen N,Dehnen JA,Soares E,van Velthoven AJH,Nuijts RMMA,Dickman MM,LaPointe VLS

Published figure using CKS2 monoclonal antibody (Product # 37-0300) in Immunocytochemistry

Fri Nov 05 00:00:00 UTC 2021

Single cell transcriptomics reveals the heterogeneity of the human cornea to identify novel markers of the limbus and stroma.

Scientific reports

Català P,Groen N,Dehnen JA,Soares E,van Velthoven AJH,Nuijts RMMA,Dickman MM,LaPointe VLS

Published figure using CKS2 monoclonal antibody (Product # 37-0300) in Immunocytochemistry

Fri Nov 05 00:00:00 UTC 2021

Mitochondrial Function of CKS2 Oncoprotein Links Oxidative Phosphorylation with Cell Division in Chemoradioresistant Cervical Cancer.

Neoplasia (New York, N.Y.)

Jonsson M,Fjeldbo CS,Holm R,Stokke T,Kristensen GB,Lyng H

37-0300 was used in Immunohistochemistry to investigate whether CDK regulatory subunit 2 has a mitochondrial function that augments tumour aggressiveness.

Mon Apr 01 00:00:00 UTC 2019

Mitochondrial Function of CKS2 Oncoprotein Links Oxidative Phosphorylation with Cell Division in Chemoradioresistant Cervical Cancer.

Neoplasia (New York, N.Y.)

Jonsson M,Fjeldbo CS,Holm R,Stokke T,Kristensen GB,Lyng H

37-0300 was used in Immunohistochemistry to investigate whether CDK regulatory subunit 2 has a mitochondrial function that augments tumour aggressiveness.

Mon Apr 01 00:00:00 UTC 2019

The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability.

Biochimica et biophysica acta. Molecular cell research

Grey W,Ivey A,Milne TA,Haferlach T,Grimwade D,Uhlmann F,Voisset E,Yu V

37-0300 was used in Western Blotting to uncover a novel regulatory pathway for MLL1, which may open a new therapeutic approach to MLLr leukaemia.

Mon Jan 01 00:00:00 UTC 2018

Upregulation of the cycline kinase subunit CKS2 increases cell proliferation rate in gastric cancer.

Journal of cancer research and clinical oncology

Kang MA,Kim JT,Kim JH,Kim SY,Kim YH,Yeom YI,Lee Y,Lee HG

Mon Jun 01 00:00:00 UTC 2009

Upregulation of the cycline kinase subunit CKS2 increases cell proliferation rate in gastric cancer.

Journal of cancer research and clinical oncology

Kang MA,Kim JT,Kim JH,Kim SY,Kim YH,Yeom YI,Lee Y,Lee HG

Mon Jun 01 00:00:00 UTC 2009

Gene expression of cyclin-dependent kinase subunit Cks2 is repressed by the tumor suppressor p53 but not by the related proteins p63 or p73.

FEBS letters

Rother K,Dengl M,Lorenz J,Tschöp K,Kirschner R,Mössner J,Engeland K

37-0300 was used in western blot to identify Cks2 as a transcriptional target downregulated by p53

Tue Mar 20 00:00:00 UTC 2007

Expression of cyclin-dependent kinase subunit 1 (Cks1) is regulated during the cell cycle by a CDE/CHR tandem element and is downregulated by p53 but not by p63 or p73.

Cell cycle (Georgetown, Tex.)

Rother K,Li YY,Tschöp K,Kirschner R,Müller GA,Mössner J,Engeland K

Sun Apr 01 00:00:00 UTC 2007

Expression of cyclin-dependent kinase subunit 1 (Cks1) is regulated during the cell cycle by a CDE/CHR tandem element and is downregulated by p53 but not by p63 or p73.

Cell cycle (Georgetown, Tex.)

Rother K,Li YY,Tschöp K,Kirschner R,Müller GA,Mössner J,Engeland K

Sun Apr 01 00:00:00 UTC 2007

Gene expressions and copy numbers associated with metastatic phenotypes of uterine cervical cancer.

BMC genomics

Lyng H,Brøvig RS,Svendsrud DH,Holm R,Kaalhus O,Knutstad K,Oksefjell H,Sundfør K,Kristensen GB,Stokke T

37-0300 was used in immunohistochemistry - paraffin section to study genes associated with metastatic phenotypes of locally advanced cervical carcinomas

Fri Oct 20 00:00:00 UTC 2006

Bioinformatics

Protein Aliases: CDC28 protein kinase 2; CKS-2; CKS1(S. cerevisiae Cdc28/Cdc2 kinase subunit) homolog-2; Cyclin-dependent kinases regulatory subunit 2; RP11-8C21.2

View more View less

Gene Aliases: CKS2; CKSHS2

View more View less

UniProt ID: (Human) P33552

View more View less

Entrez Gene ID: (Human) 1164

View more View less

Function(s)

protein binding protein kinase binding histone binding ubiquitin binding cyclin-dependent protein serine/threonine kinase activator activity

Process(es)

meiosis I regulation of mitotic cell cycle positive regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of transcription, DNA-templated cell division

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

CKS2 Monoclonal Antibody (1F7G5)

CKS2 Antibody (37-0300) in WB

Product Details

37-0300

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

ELISA (ELISA)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!