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Invitrogen
CLASP1 Monoclonal Antibody (KT66)
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Product Details
MA5-47708
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
KT66
Immunogen
Clone KT66 was generated from a GST fusion protein containing the C-terminus of mouse CLASP1. This sequence is highly conserved in human, rat, chicken, and fish CLASP1, and has low homology to CLASP2.
Conjugate
Form
Liquid
Concentration
~1.0 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2942689
Product Specific Information
The antibody detects a 161 kDa* protein corresponding to the molecular mass of CLASP1 on SDS-PAGE immunoblots of human HeLa, mouse brain, and rat PC12 cells. The antibody also detects CLASP1 by immunocytochemistry in HeLa cells.
Target Information
CLASPs, such as CLASP1, are nonmotor microtubule-associated proteins that interact with CLIPs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CLIP-associating protein 1; cytoplasmic linker associated protein 1; Cytoplasmic linker-associated protein 1; hOrbit1; multiple asters 1; Multiple asters homolog 1; Protein Orbit homolog 1
Gene Aliases: 1700030C23Rik; 5730583A19Rik; B130045P17Rik; CLASP1; CLASP1alpha; KIAA0622; MAST1
UniProt ID: (Human) Q7Z460, (Mouse) Q80TV8
Entrez Gene ID: (Human) 23332, (Mouse) 76707, (Rat) 304740
G2/M transition of mitotic cell cycle
microtubule cytoskeleton organization
microtubule bundle formation
vesicle targeting
microtubule nucleation
negative regulation of microtubule depolymerization
Golgi organization
mitotic spindle organization
sister chromatid cohesion
establishment or maintenance of cell polarity
exit from mitosis
regulation of gastrulation
positive regulation of epithelial cell migration
regulation of epithelial to mesenchymal transition
astral microtubule organization
microtubule organizing center organization
negative regulation of microtubule polymerization or depolymerization
positive regulation of microtubule polymerization
microtubule anchoring
establishment of mitotic spindle localization
positive regulation of exocytosis
establishment of spindle orientation
cell division
negative regulation of stress fiber assembly
regulation of focal adhesion assembly
regulation of microtubule cytoskeleton organization
positive regulation of extracellular matrix disassembly
establishment of epithelial cell polarity
mitotic spindle assembly
negative regulation of wound healing, spreading of epidermal cells
positive regulation of basement membrane assembly involved in embryonic body morphogenesis
cell cycle
mitotic nuclear division
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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