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CLCKB/CLCKA Polyclonal Antibody
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Product Details
OSC00251W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from the n-terminal region of human CLCKB conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: CLCKB/A.
Target Information
This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Chloride channel Ka; Chloride channel Kb; Chloride channel protein ClC-Ka; Chloride channel protein ClC-Kb; chloride channel, kidney, A; chloride channel, kidney, B; chloride channel, voltage-sensitive Ka; chloride channel, voltage-sensitive Kb; ClC-K1; ClC-K2; CLCNK; hClC-Kb
Gene Aliases: ClC-K1; ClC-K2; ClC-Kb; CLCK1; CLCKB; CLCNKA; CLCNKB; hClC-Ka
UniProt ID: (Human) P51800, (Human) P51801
Entrez Gene ID: (Human) 1187, (Human) 1188
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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