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Abnova
CLCN2 Monoclonal Antibody (3E1)
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CLCN2 Antibody (H00001181-M01) in WB
Western blot analysis of CLCN2 over-expressed 293 cell line, cotransfected with CLCN2 Validated Chimera RNAi (Cat # H00001181-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with CLCN2 monoclonal antibody (M01), clone 3E1 (Cat # H00001181-M01). GAPDH ( 36.1 kDa ) used as specificity and loading control.
Product Details
H00001181-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3E1
Immunogen
CLCN2 (AAH21578.1, 38 a.a. approximately 387 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: TVSTAVIVFE LTGQIAHILP VMIVVILANA VAQSLQPSLY DSIIRIKKLP YLPELGWGRH QQYRVRVEDI MVRDVPHVAL SCTFRDLRLA LHRTKGRMLA LVESPESMIL LGSIERSQVV ALLGAQLSPA RRRQHMQERR ATQTSPLSDQ EGPPTPEASV CFQVNTEDSA FPAARGETHK PLKPALKRGP SVTRNLGESP TGSAESAGIA LRSLFCGSPP PEAASEKLES CEKRKLKRVR ISLASDADLE GEMSPEETHT IFSLLGVDHA YVTSIGRLIG IVTLKELRKA IEGSVTAQGV KVRPPLASFR DSATSSSDTE TTEVHALWGP HSRHGLPREG SPSDSDDKCQ
Target Information
The transmembrane protein encoded by this gene is a voltage-gated chloride channel that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: chloride channel 2; Chloride channel protein 2; chloride channel, voltage-sensitive 2; CIC 2; CIC2; ClC-2; EG13
Gene Aliases: CIC-2; clC-2; CLC2; CLCN2; ECA2; ECA3; EGI11; EGI3; EGMA; EJM6; EJM8; LKPAT
UniProt ID: (Human) P51788
Entrez Gene ID: (Human) 1181
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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