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Antibody detects endogenous levels of total CLEC4A.
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
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Protein Aliases: C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6; C-type lectin DDB27; C-type lectin domain family 4 member A; C-type lectin domain family 4, member A; C-type lectin domain family 4, member A2; C-type lectin superfamily member 6; CD367; Dendritic cell immunoreceptor; dendritic cell inhibitory receptor 1; dendritic cell inhibitory receptor 2; immunoreceptor; Lectin-like immunoreceptor
Gene Aliases: CD367; CLEC4A; Clec4a2; CLECSF6; DCIR; Dcir1; Dcir2; DDB27; HDCGC13P; LLIR
UniProt ID: (Human) Q9UMR7, (Mouse) Q9QZ15
Entrez Gene ID: (Human) 50856, (Rat) 474143, (Mouse) 26888, (Rat) 297584
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