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Product Details
MA5-33341
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
WEN43
Immunogen
Rat mincle-Fcgamma2b fusion protein
Conjugate
Form
Liquid
Concentration
100 µg/mL
Purification
Protein G
Storage buffer
PBS with 0.1% BSA
Contains
no preservative
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2815479
Product Specific Information
Product is supplied at 1 mL (100 µL/mL). Application notes: Flow Cytometry - This anitbody stains the extracellular domain of Mincle transfected 293 cells. It does not bind to other receptors in the rat APLEC family. Functional Assay - This antibody can act complementary in the inhibition of phagocytosis.
Positive control: BW5417 or 293T cells.
Target Information
CLEC4E encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-type lectin domain family 4 member E; C-type lectin superfamily member 9; immunoreceptor; Macrophage-inducible C-type lectin; Mincle
Gene Aliases: Clec4e; Clecsf9; Mincle
UniProt ID: (Rat) Q67EQ1
Entrez Gene ID: (Rat) 450223
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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