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Immunogen sequence: AYPCPCDIGH RLEYGGLGRE VQVEHIKAYV TKSPVDAGKA VIVIQDIFGW QLPNTRYIAD MISGNGYTTI VPDFFVG
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 88%.
CMBL is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Carboxymethylenebutenolidase homolog; carboxymethylenebutenolidase homolog (Pseudomonas); carboxymethylenebutenolidase-like (Pseudomonas)
Gene Aliases: CMBL; JS-1
UniProt ID: (Human) Q96DG6
Entrez Gene ID: (Human) 134147
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