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Invitrogen
CMG1 Polyclonal Antibody
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FIGURE: 1 / 2
CMG1 Antibody (PA5-142370) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of CMG1 in U251 cells using CMG1 Polyclonal Antibody (Product # PA5-142370). Cells were fixed with paraformaldehyde, permeabilized with 0.15% Triton, and incubated with the primary antibody for 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (4 µg/mL), showing cytoplasmic and Golgi apparatus staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (4 µg/mL).
Product Details
PA5-142370
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence CKTIVDALHSTSGN (aa 588-600).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2933019
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Capillary morphogenesis gene 1 protein; capillary morphogenesis protein 1; CMG-1; coiled-coil domain containing 2; Coiled-coil domain-containing protein 2; intraflagellar transport 74 homolog; Intraflagellar transport protein 74 homolog
Gene Aliases: CCDC2; CMG-1; CMG1; IFT74
UniProt ID: (Human) Q96LB3
Entrez Gene ID: (Human) 80173
keratinocyte development
Notch signaling pathway
determination of left/right symmetry
heart development
positive regulation of cell adhesion mediated by integrin
intraciliary transport involved in cilium morphogenesis
cilium assembly
positive regulation of transcription from RNA polymerase II promoter
negative regulation of epithelial cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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