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Invitrogen
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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Chemokines are members of a superfamily of small inducible, secreted, pro-inflammatory cytokines. Members of the chemokine-like factor superfamily (CKLFSF) share similarities with both chemokine and transmembrane 4 superfamilies of signaling molecules. As a member of the CKLFSF family of proteins, CMTM1 (CKLF-like MARVEL transmembrane domain-containing protein 1), also known as CKLFSF1 (Chemokine-like factor superfamily member 1), is a 169 amino acid multi-pass membrane protein that is highly expressed in testis, therefore probably playing a role in spermatogenesis or testicular development. CMTM1 contains a CC-chemokine motif and four transmembrane segments. The gene encoding CMTM1 resides in a tight gene cluster on human chromosome 16 with CKLF, CMTM2, CMTM3 and CMTM4. There are at least sixteen isoforms of CMTM1 that are produced as a result of alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chemokine-like factor super family 1; chemokine-like factor superfamily 1; Chemokine-like factor superfamily member 1; chemokine-like factor-like protein CKLFH1; CKLF-like MARVEL transmembrane domain containing 1; CKLF-like MARVEL transmembrane domain-containing protein 1
Gene Aliases: CHLFH1a; CKLFH; CKLFH1; CKLFSF1; CMTM1
UniProt ID: (Human) Q8IZ96
Entrez Gene ID: (Human) 113540, (Rat) 291823, (Mouse) 100504164
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