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CNGA3 Antibody (MA3-901) in ICC/IF
Immunofluorescent analysis using CNGA3 Monoclonal Antibody (CNC 9C1) (Product # MA3-901) shows CNGA3 staining in B-3 Cells (green). F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with an antibody recognizing CNGA3 (Product # MA3-901) at a dilution of 1:20 over night at 4°C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody (Product # 35503, Goat Anti-Mouse). Imag... View More
Product Details
MA3-901
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
CNC 9C1
Immunogen
MBP-fusion protein of the C-terminal region of the rat a2 subunit (amino acids K581-D670)
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2081689
Product Specific Information
MA3-901 detects CNG channel from human, mouse and rat samples.
MA3-901 has been successfully used in Western blotting and immunohistochemistry procedures. By Western blot MA3-901 detects a band representing CNG channel. MA3-901 is specific to the a2 subunit of the CNG channel.
The MA3-901 immunogen is a MBP-fusion protein of the C-terminal region of the rat a2 subunit (amino acids K581-D670)
Target Information
This gene encodes a member of the cyclic nucleotide-gated cation channel protein family which is required for normal vision and olfactory signal transduction. Mutations in this gene are associated with achromatopsia (rod monochromacy) and color blindness. Two alternatively spliced transcripts encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cng channel; CNG channel alpha-3; CNG-3; CNGalpha2; CNGgust; cone photoreceptor cGMP-gated channel alpha subunit; cone photoreceptor cGMP-gated channel subunit alpha; Cone photoreceptor cGMP-gated channel subunit alpha-3; cyclic nucleotide-gated cation channel alpha-3; Cyclic nucleotide-gated channel alpha-3; Gustatory cyclic nucleotide-gated cation channel
Gene Aliases: ACHM2; CCNC1; CCNCa; CCNCalpha; CNCG3; CNG3; CNGA3
UniProt ID: (Human) Q16281, (Mouse) Q9JJZ8
Entrez Gene ID: (Human) 1261, (Mouse) 12790, (Rat) 85257
intracellular cAMP activated cation channel activity
intracellular cGMP activated cation channel activity
voltage-gated potassium channel activity
protein C-terminus binding
ligand-gated ion channel activity
cGMP binding
nucleotide binding
ion channel activity
intracellular cyclic nucleotide activated cation channel activity
protein binding
signal transducer activity
transport
cation transport
signal transduction
visual perception
response to corticosteroid
response to magnesium ion
regulation of membrane potential
response to cAMP
potassium ion transmembrane transport
ion transport
ion transmembrane transport
regulation of ion transmembrane transport
retinal cone cell development
response to stimulus
transmembrane transport
cation transmembrane transport
phototransduction, visible light
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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