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Product Details
PA5-68969
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide directed towards the middle region of human CNOT8 (aa 15-64)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2691388
Product Specific Information
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Target Information
CNOT8 (CCR4-NOT transcription complex subunit 8), also known as CALIF or POP2, is a 292 amino acid protein that localizes to both the nucleus and the cytoplasm and functions as part of the CCR-NOT complex. Expressed ubiquitously, CNOT8 plays a role in transcriptional regulation for a diverse set of processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CCR4-associated factor 8; CCR4-NOT transcription complex subunit 8; h CAF1-like protein
Gene Aliases: 1500015I04Rik; 1810022F04Rik; AA536816; AU015770; AU043059; Cnot8
UniProt ID: (Mouse) Q9D8X5
Entrez Gene ID: (Mouse) 69125
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of translation
positive regulation of cell proliferation
gene silencing by RNA
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
positive regulation of mRNA catabolic process
RNA phosphodiester bond hydrolysis, exonucleolytic
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