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CNPase Polyclonal Antibody

CNPase Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CNPase Antibody (13427-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded mouse brain tissue slide using 13427-1-AP ( CNPase antibody at dilution of 1:50 (under 40x lens).

CNPase Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

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Product Details

13427-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 4 publications 4 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CNPase Fusion Protein Ag4227 (1-421 aa encoded by BC028040)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MNRGFSRKS HTFLPKIFFR KMSSSGAKDK PELQFPFLQD EDTVATLLEC KTLFILRGLP GSGKSTLARV IVDKYRDGTK MVSADAYKIT PGARGAFSEE YKRLDEDLAA YCRRRDIRIL VLDDTNHERE RLEQLFEMAD QYQYQVVLVE PKTAWRLDCA QLKEKNQWQL SADDLKKLKP GLEKDFLPLY FGWFLTKKSS ETLRKAGQVF LEELGNHKAF KKELRQFVPG DEPREKMDLV TYFGKRPPGV LHCTTKFCDY GKAPGAEEYA QQDVLKKSYS KAFTLTISAL FVTPKTTGAR VELSEQQLQL WPSDVDKLSP TDNLPRGSRA HITLGCAADV EAVQTGLDLL EILRQEKGGS RGEEVGELSR GKLYSLGNGR WMLTLAKNME VRAIFTGYYG KGKPVPTQGS RKGGALQSCT II (1-421 aa encoded by BC028040)

Target Information

CNP may participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

T0901317, a liver X receptor agonist, ameliorates perinatal white matter injury induced by ischemia and hypoxia in neonatal rats.

Neuroscience letters

Gao T,Qian T,Wang T,Su Y,Qiu H,Tang W,Xing Q,Wang L

Tue Jan 10 00:00:00 UTC 2023

Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.

The Journal of clinical investigation

Liu Z,Yan M,Lei W,Jiang R,Dai W,Chen J,Wang C,Li L,Wu M,Nian X,Li D,Sun D,Lv X,Wang C,Xie C,Yao L,Wu C,Hu J,Xiao N,Mo W,Wang Z,Zhang L

Fri Apr 01 00:00:00 UTC 2022

TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration.

Nature neuroscience

Xie M,Liu YU,Zhao S,Zhang L,Bosco DB,Pang YP,Zhong J,Sheth U,Martens YA,Zhao N,Liu CC,Zhuang Y,Wang L,Dickson DW,Mattson MP,Bu G,Wu LJ

Sat Jan 01 00:00:00 UTC 2022

Sodium selenite promotes neurological function recovery after spinal cord injury by inhibiting ferroptosis.

Neural regeneration research

Chen YX,Zuliyaer T,Liu B,Guo S,Yang DG,Gao F,Yu Y,Yang ML,Du LJ,Li JJ

Thu Dec 01 00:00:00 UTC 2022

Leucoencephalopathy with Pigmented Glia in a Horse with Recurrent Convulsive Seizures.

Journal of comparative pathology

Sakurai M,Isshiki S,Sasaki N,Sakai Y,Yamada Y,Morimoto M

Mon Nov 01 00:00:00 UTC 2021

Neural Stem Cells Overexpressing Nerve Growth Factor Improve Functional Recovery in Rats Following Spinal Cord Injury via Modulating Microenvironment and Enhancing Endogenous Neurogenesis.

Frontiers in cellular neuroscience

Wang L,Gu S,Gan J,Tian Y,Zhang F,Zhao H,Lei D

Tue Dec 21 00:00:00 UTC 2021

Neural Stem Cells Overexpressing Nerve Growth Factor Improve Functional Recovery in Rats Following Spinal Cord Injury via Modulating Microenvironment and Enhancing Endogenous Neurogenesis.

Frontiers in cellular neuroscience

Wang L,Gu S,Gan J,Tian Y,Zhang F,Zhao H,Lei D

Tue Dec 21 00:00:00 UTC 2021

Transfer of α-synuclein from neurons to oligodendrocytes triggers myelin sheath destruction in methamphetamine administration mice.

Toxicology letters

Ding J,Huang J,Xia B,Hu S,Fan H,Dai J,Li Z,Wang J,Le C,Qiu P,Wang Y

Mon Nov 01 00:00:00 UTC 2021

Profiling analysis reveals the potential contribution of long non-coding RNAs to preterm white matter injury.

Life sciences

Wang D,Ye X,Xie H,Liu Y,Xu Y,Wang Y,Zhou Y,Zhou N,Wang J

Sat Aug 15 00:00:00 UTC 2020

Cuprizone-Induced Demyelination in Mouse Hippocampus Is Alleviated by Ketogenic Diet.

Journal of agricultural and food chemistry

Liu C,Zhang N,Zhang R,Jin L,Petridis AK,Loers G,Zheng X,Wang Z,Siebert HC

Wed Oct 07 00:00:00 UTC 2020

2',3'-cyclic nucleotide 3'-phosphodiesterases inhibit hepatitis B virus replication.

PloS one

Ma H,Zhao XL,Wang XY,Xie XW,Han JC,Guan WL,Wang Q,Zhu L,Pan XB,Wei L

Tue Aug 26 00:00:00 UTC 2014

2',3'-cyclic nucleotide 3'-phosphodiesterases inhibit hepatitis B virus replication.

PloS one

Ma H,Zhao XL,Wang XY,Xie XW,Han JC,Guan WL,Wang Q,Zhu L,Pan XB,Wei L

Tue Aug 26 00:00:00 UTC 2014

2',3'-cyclic nucleotide 3'-phosphodiesterases inhibit hepatitis B virus replication.

PloS one

Ma H,Zhao XL,Wang XY,Xie XW,Han JC,Guan WL,Wang Q,Zhu L,Pan XB,Wei L

Tue Aug 26 00:00:00 UTC 2014

2',3'-cyclic nucleotide 3'-phosphodiesterases inhibit hepatitis B virus replication.

PloS one

Ma H,Zhao XL,Wang XY,Xie XW,Han JC,Guan WL,Wang Q,Zhu L,Pan XB,Wei L

Tue Aug 26 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: 2', 3' cyclic nucleotide 3' phosphohydrolase; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; CNPase; cyclic nucleotide phosphodiesterase 1

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Gene Aliases: CNP; Cnp-1; CNP1; CNPase; CNPF; CNPI; CNPII

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UniProt ID: (Human) P09543, (Mouse) P16330, (Rat) P13233

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Entrez Gene ID: (Human) 1267, (Mouse) 12799, (Rat) 25275

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Function(s)

RNA binding 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity cyclic nucleotide binding hydrolase activity

Process(es)

microtubule cytoskeleton organization axonogenesis adult locomotory behavior cyclic nucleotide catabolic process response to toxic substance regulation of mitochondrial membrane permeability oligodendrocyte differentiation chemical synaptic transmission aging substantia nigra development forebrain development response to lipopolysaccharide

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CNPase Polyclonal Antibody

CNPase Antibody (13427-1-AP) in IHC (P)

Product Details

13427-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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