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Invitrogen
COBRA1 Polyclonal Antibody
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Product Details
PA5-54169
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human COBRA1. Recombinant protein control fragment (Product #RP-93093).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2639998
Product Specific Information
Immunogen sequence: KETLTNCTEP LKAIEQFQTE NGVLLPSLQS ALPFLDLHGT PRLEFHQSVF DELRDKLLER VSAIASEGKA EERYKKLED
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2), either NELFC or NELFD (TH1L), and NELFE (RDBP), a heterodimer of SPT4 (SUPT4H1), to cause transcriptional pausing of RNA polymerase II (Narita et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cofactor of BRCA1; DKFZp586B0519; Negative elongation factor B; negative elongation factor complex member B, Cobra1; negative elongation factor protein B; NELF-B; ortholog of human cofactor of BRCA1 (COBRA1); RP13-122B23.3
Gene Aliases: A730008L03Rik; AB041607; AI663983; COBRA1; KIAA1182; MNCb-5210; NELF-B; NELFB; RGD1307832
UniProt ID: (Human) Q8WX92, (Mouse) Q8C4Y3
Entrez Gene ID: (Human) 25920, (Mouse) 58202, (Rat) 311796
transcription, DNA-templated
regulation of transcription, DNA-templated
negative regulation of transcription, DNA-templated
translational elongation
biological_process
transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
negative regulation of transcription elongation from RNA polymerase II promoter
positive regulation of viral transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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