Proteintech

COG3 Polyclonal Antibody

COG3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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COG3 Antibody (11130-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human prostate cancer using 11130-1-AP (COG3 antibody) at dilution of 1:100 (under 10x lens).

COG3 Antibody in Immunoprecipitation (IP)

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Product Details

11130-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

COG3 Fusion Protein Ag1610 (1-280 aa encoded by BC038953)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAEAALLLL PEAAAERDAR EKLALWDRRP DTTAPLTDRQ TDSVLELKAA AENLPVPAEL PIEDLCSLTS QSLPIELTSV VPESTEDILL KGFTSLGMEE ERIETAQQFF SWFAKLQTQM DQDEGTKYRQ MRDYLSGFQE QCDAILNDVN SALQHLESLQ KQYLFVSNKT GTLHEACEQL LKEQSELVDL AENIQQKLSY FNELETINTK LNSPTLSVNS DGFIPMLAKL DDCITYISSH PNFKDYPIYL LKFKQCLSKA LHLMKTYTVN TLQTLTSQLL K (1-280 aa encoded by BC038953)

Target Information

This gene encodes a component of the conserved oligomeric Golgi (COG) complex which is composed of eight different subunits and is required for normal Golgi morphology and localization. Defects in the COG complex result in multiple deficiencies in protein glycosylation. The protein encoded by this gene is involved in ER-Golgi transport.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Verteporfin Inhibits PD-L1 through Autophagy and the STAT1-IRF1-TRIM28 Signaling Axis, Exerting Antitumor Efficacy.

Cancer immunology research

Liang J,Wang L,Wang C,Shen J,Su B,Marisetty AL,Fang D,Kassab C,Jeong KJ,Zhao W,Lu Y,Jain AK,Zhou Z,Liang H,Sun SC,Lu C,Xu ZX,Yu Q,Shao S,Chen X,Gao M,Claret FX,Ding Z,Chen J,Chen P,Barton MC,Peng G,Mills GB,Heimberger AB

Wed Jul 01 00:00:00 UTC 2020

Verteporfin Inhibits PD-L1 through Autophagy and the STAT1-IRF1-TRIM28 Signaling Axis, Exerting Antitumor Efficacy.

Cancer immunology research

Wed Jul 01 00:00:00 UTC 2020

A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer.

Cancer cell

Peng X,Xu X,Wang Y,Hawke DH,Yu S,Han L,Zhou Z,Mojumdar K,Jeong KJ,Labrie M,Tsang YH,Zhang M,Lu Y,Hwu P,Scott KL,Liang H,Mills GB

Mon May 14 00:00:00 UTC 2018

A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer.

Cancer cell

Peng X,Xu X,Wang Y,Hawke DH,Yu S,Han L,Zhou Z,Mojumdar K,Jeong KJ,Labrie M,Tsang YH,Zhang M,Lu Y,Hwu P,Scott KL,Liang H,Mills GB

Mon May 14 00:00:00 UTC 2018

Systematic Functional Annotation of Somatic Mutations in Cancer.

Cancer cell

Ng PK,Li J,Jeong KJ,Shao S,Chen H,Tsang YH,Sengupta S,Wang Z,Bhavana VH,Tran R,Soewito S,Minussi DC,Moreno D,Kong K,Dogruluk T,Lu H,Gao J,Tokheim C,Zhou DC,Johnson AM,Zeng J,Ip CKM,Ju Z,Wester M,Yu S,Li Y,Vellano CP,Schultz N,Karchin R,Ding L,Lu Y,Cheung LWT,Chen K,Shaw KR,Meric-Bernstam F,Scott KL,Yi S,Sahni N,Liang H,Mills GB

Mon Mar 12 00:00:00 UTC 2018

Systematic Functional Annotation of Somatic Mutations in Cancer.

Cancer cell

Mon Mar 12 00:00:00 UTC 2018

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers.

Cancer cell

Han L,Diao L,Yu S,Xu X,Li J,Zhang R,Yang Y,Werner HMJ,Eterovic AK,Yuan Y,Li J,Nair N,Minelli R,Tsang YH,Cheung LWT,Jeong KJ,Roszik J,Ju Z,Woodman SE,Lu Y,Scott KL,Li JB,Mills GB,Liang H

Mon Oct 12 00:00:00 UTC 2015

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers.

Cancer cell

Han L,Diao L,Yu S,Xu X,Li J,Zhang R,Yang Y,Werner HMJ,Eterovic AK,Yuan Y,Li J,Nair N,Minelli R,Tsang YH,Cheung LWT,Jeong KJ,Roszik J,Ju Z,Woodman SE,Lu Y,Scott KL,Li JB,Mills GB,Liang H

Mon Oct 12 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: COG complex subunit 3; component of oligomeric golgi complex 2; Component of oligomeric Golgi complex 3; Conserved oligomeric Golgi complex subunit 3; p94; tethering factor SEC34; Vesicle-docking protein SEC34 homolog

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Gene Aliases: COG3; E430004N23; SEC34

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UniProt ID: (Human) Q96JB2

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Entrez Gene ID: (Human) 83548, (Mouse) 338337, (Rat) 361073

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Function(s)

protein binding protein transporter activity

Process(es)

retrograde transport, vesicle recycling within Golgi protein glycosylation transport intracellular protein transport ER to Golgi vesicle-mediated transport retrograde vesicle-mediated transport, Golgi to ER intra-Golgi vesicle-mediated transport Golgi organization protein transport protein localization to organelle protein stabilization

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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COG3 Polyclonal Antibody

COG3 Antibody (11130-1-AP) in IHC (P)

Product Details

11130-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunoprecipitation (IP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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