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Invitrogen
COL4A6 Polyclonal Antibody
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Product Details
PA5-50939
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from the C-terminal region of human COL4A6.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2636387
Product Specific Information
COL4A6 Polyclonal Antibody detects endogenous levels of COL4A6 protein.
Target Information
Type I collagen, the fibrillar collagen found in most connective tissues, and the only component of the collagen found in cartilage. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Collagen 4; Collagen alpha-6(IV) chain; collagen IV, alpha-6 polypeptide; collagen of basement membrane, alpha-6; collagen, type IV, alpha 6; dJ889N15.4 (Collagen Alpha 6(IV)); procollagen type IV alpha 6; procollagen, type IV, alpha 6
Gene Aliases: BB116301; COL4A6; CXDELq22.3; DELXq22.3; DFNX6
UniProt ID: (Human) Q14031
Entrez Gene ID: (Human) 1288, (Mouse) 94216, (Rat) 363458
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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