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Invitrogen
COLEC12 Polyclonal Antibody
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Product Details
PA5-99859
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human COLEC12(Accession Q5KU26), corresponding to amino acid residues I666-Q716.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2818792
Product Specific Information
Antibody detects endogenous levels of total COLEC12.
Target Information
This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CL-P1; Collectin placenta protein 1; collectin sub-family member 12; Collectin-12; hCL-P1; Nurse cell scavenger receptor 2; Scavenger receptor class A member 4; scavenger receptor class A, member 4; Scavenger receptor with C-type lectin
Gene Aliases: CL-P1; CLP1; COLEC12; NSR2; SCARA4; SRCL
UniProt ID: (Human) Q5KU26, (Rat) Q4V885, (Mouse) Q8K4Q8
Entrez Gene ID: (Human) 81035, (Rat) 361289, (Mouse) 140792
receptor-mediated endocytosis
phagocytosis, recognition
defense response
carbohydrate mediated signaling
toll-like receptor 3 signaling pathway
innate immune response
protein homooligomerization
positive regulation of cell adhesion molecule production
cellular response to exogenous dsRNA
pattern recognition receptor signaling pathway
immune response
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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