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Positive Control: Human skeletal muscle tissue, Rat bone marrow, A431, HCT116, rat heart tissue, human liver cancer tissue, human breast tissue, human pancreas tissue, mouse kidney tissue, mouse heart tissue, 293.
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: COP9 complex subunit 3; COP9 constitutive photomorphogenic homolog subunit 3; COP9 signalosome complex subunit 3; COPS 3; JAB1-containing signalosome subunit 3; SGN3; signalosome subunit 3
Gene Aliases: COPS3; CSN3; SGN3
UniProt ID: (Human) Q9UNS2
Entrez Gene ID: (Human) 8533
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