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Invitrogen
COQ7 Polyclonal Antibody
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FIGURE: 1 / 2
COQ7 Antibody (PA5-106348) in ICC/IF
Immunofluorescent analysis of COQ7 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and COQ7 polyclonal antibody (Product # PA5-106348) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-106348
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human COQ7(Accession Q99807), corresponding to amino acid residues F34-Q84.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2854024
Product Specific Information
Antibody detects endogenous levels of total COQ7.
Target Information
The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5-demethoxyubiquinone hydroxylase; 5-demethoxyubiquinone hydroxylase, mitochondrial; Coenzyme q (ubiquinone) biosynthetic enzyme (DHPB methyltransferase) 7; coenzyme Q biosynthesis protein 7 homolog; coenzyme Q7 homolog, ubiquinone; COQ7 coenzyme Q, 7 homolog ubiquinone; demethyl-Q 7; DMQ hydroxylase; placental protein KG-20; Timing protein clk-1 homolog; Ubiquinone biosynthesis monooxygenase COQ7; ubiquinone biosynthesis protein COQ7 homolog
Gene Aliases: CAT5; CLK-1; CLK1; COQ10D8; COQ7
UniProt ID: (Human) Q99807, (Mouse) P97478
Entrez Gene ID: (Human) 10229, (Rat) 25249, (Mouse) 12850
age-dependent response to oxidative stress
in utero embryonic development
neural tube formation
ubiquinone biosynthetic process
response to oxidative stress
determination of adult lifespan
neurogenesis
respiratory electron transport chain
cellular response to oxidative stress
response to drug
mitochondrial ATP synthesis coupled electron transport
oxidation-reduction process
mitochondrion morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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