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COX18 Antibody (PA5-119537) in WB
Western blot analysis of COX18 in MCF-7 whole cell and membrane extracts (30 µg). Sample was separated with 10% SDS-PAGE, incubated with polyclonal COX18 antibody (Product # PA5-119537) at a dilution of 1:1000, and followed by HRP-conjugated anti-rabbit IgG.
Product Details
PA5-119537
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human COX18. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.28 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2913110
Product Specific Information
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Target Information
COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain. Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: COX18 cytochrome c oxidase assembly factor; COX18Hs; cytochrome c oxidase assembly homolog 18; Cytochrome c oxidase assembly protein 18; Cytochrome c oxidase assembly protein COX18, mitochondrial
Gene Aliases: COX18; COX18HS; OXA1L2
UniProt ID: (Human) Q8N8Q8
Entrez Gene ID: (Human) 285521
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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