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Invitrogen
CPEB1 Polyclonal Antibody
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Product Details
PA5-85484
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human CPEB1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792624
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (96%), Rat (95%), Xenopus laevis (81%), Pig (98%), Chicken (87%), Rhesus Monkey (99%).
Positive Control: HepG2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the nuclear membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the nuclear membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CEBP; CPE-binding protein 1; CPE-BP1; Cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; MGC34136; MGC60106
Gene Aliases: CPE-BP1; CPEB; CPEB-1; CPEB1; h-CPEB; hCPEB-1
UniProt ID: (Human) Q9BZB8
Entrez Gene ID: (Human) 64506
mRNA processing
translation
negative regulation of cell proliferation
positive regulation of neuron projection development
positive regulation of cell migration
cellular response to insulin stimulus
positive regulation of translation
mRNA transport
positive regulation of nitric-oxide synthase biosynthetic process
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
cellular response to hypoxia
negative regulation of cytoplasmic translation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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