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CPNE1 Antibody (PA5-117887) in WB
Western Blot using CPNE1 Polyclonal Antibody (Product # PA5-117887) at 1:500 dilution. Lane A: A431 Whole Cell Lysate. Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG H&L (DyLight™ 800) at 1:10,000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 59 kDa. Observed band size: 59 kDa. (We are unsure of the identity of these extra bands).
Product Details
PA5-117887
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Copine I/CPN1/CPNE1 Protein
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2902495
Target Information
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Alternate splicing results in multiple transcript variants encoding different proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chromobindin 17; Copine I; Copine-1; MGC1142; OTTHUMP00000030775; OTTHUMP00000030776
Gene Aliases: COPN1; CPN1; CPNE1
UniProt ID: (Human) Q99829
Entrez Gene ID: (Human) 8904
transcription, DNA-templated
regulation of transcription, DNA-templated
proteolysis
lipid metabolic process
negative regulation of gene expression
vesicle-mediated transport
regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of DNA binding
positive regulation of neuron differentiation
glycerophospholipid biosynthetic process
positive regulation of protein kinase B signaling
cellular response to calcium ion
negative regulation of NIK/NF-kappaB signaling
positive regulation of tumor necrosis factor-mediated signaling pathway
neuron projection extension
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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