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Proteintech
CPS1 Polyclonal Antibody
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Product Details
24513-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CPS1 Fusion Protein Ag21605 (1361-1500 aa encoded by BC140943)
Conjugate
Form
Liquid
Concentration
0.28 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GILIGIQQS FRPRFLGVAE QLHNEGFKLF ATEATSDWLN ANNVPATPVA WPSQEGQNPS LSSIRKLIRD GSIDLVINLP NNNTKFVHDN YVIRRTAVDS GIPLLTNFQV TKLFAEAVQK SRKVDSKSLF HYRQYSAGKA A (1361-1500 aa encoded by BC140943)
Target Information
The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: carbamoyl-phosphate synthase (ammonia); carbamoyl-phosphate synthase 1, mitochondrial; Carbamoyl-phosphate synthase [ammonia], mitochondrial; carbamoyl-phosphate synthetase 1, mitochondrial; Carbamoyl-phosphate synthetase I; carbamoylphosphate synthetase I; carbamyl phosphate synthetase I; carboamyl-phosphate synthetase 1; CPSase I
Gene Aliases: 4732433M03Rik; CPS; CPS1; CPSASE1; D1Ucla3; PHN
UniProt ID: (Human) P31327, (Mouse) Q8C196, (Rat) P07756
Entrez Gene ID: (Human) 1373, (Mouse) 227231, (Rat) 497840
aspartate carbamoyltransferase activity
carbamoyl-phosphate synthase (ammonia) activity
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
dihydroorotase activity
endopeptidase activity
calcium ion binding
protein binding
ATP binding
phospholipid binding
glutamate binding
protein complex binding
modified amino acid binding
nucleotide binding
catalytic activity
ligase activity
metal ion binding
urea cycle
glycogen catabolic process
'de novo' pyrimidine nucleobase biosynthetic process
proteolysis
arginine biosynthetic process
glutamine metabolic process
nitrogen compound metabolic process
metabolic process
triglyceride catabolic process
response to lipopolysaccharide
positive regulation of vasodilation
nitric oxide metabolic process
homocysteine metabolic process
anion homeostasis
carbamoyl phosphate biosynthetic process
liver development
glutamine catabolic process
midgut development
response to toxic substance
response to zinc ion
response to amine
response to food
response to glucagon
response to oleic acid
response to drug
response to starvation
response to amino acid
cellular response to fibroblast growth factor stimulus
response to steroid hormone
response to glucocorticoid
response to cAMP
response to growth hormone
hepatocyte differentiation
cellular response to cAMP
cellular response to glucagon stimulus
cellular response to oleic acid
response to dexamethasone
citrulline biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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