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Product Details
PA5-117057
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 331-600 of human CPSF3L (NP_0603412)
Conjugate
Form
Liquid
Concentration
4.2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2901687
Product Specific Information
Positive Samples: HeLa, SKOV3, MCF7, Mouse spleen, Rat liver
Immunogen sequence: GQSLQIFRKW AGNEKNMVIM PGYCVQGTVG HKILSGQRKL EMEGRQVLEV KMQVEYMSFS AHADAKGIMQ LVGQAEPESV LLVHGEAKKM EFLKQKIEQE LRVNCYMPAN GETVTLPTSP SIPVGISLGL LKREMAQGLL PEAKKPRLLH GTLIMKDSNF RLVSSEQALK ELGLAEHQLR FTCRVHLHDT RKEQETALRV YSHLKSVLKD HCVQHLPDGS VTVESVLLQA AAPSEDPGTK VLLVSWTYQD EELGSFLTSL LKKGLPQAPS
Target Information
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; Int11; Integrator complex subunit 11; Protein related to CPSF subunits of 68 kDa; RC-68; related to CPSF subunits 68 kDa
Gene Aliases: 2410006F12Rik; AU044035; CPSF3L; CPSF73L; INT11; INTS11; RC-68; RC68; RGD1306841
UniProt ID: (Human) Q5TA45, (Mouse) Q9CWS4, (Rat) Q3MHC2
Entrez Gene ID: (Human) 54973, (Mouse) 71957, (Rat) 298688
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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