Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 2
Peptide sequence: TESTYATTIR DSKRCRERDF LKKVHETVER GGKGAHEPEG AHLLLHGADR
Sequence homology: Cow: 100%; Dog: 100%; Goat: 77%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; Int11; Integrator complex subunit 11; Protein related to CPSF subunits of 68 kDa; RC-68; related to CPSF subunits 68 kDa
Gene Aliases: CPSF3L; CPSF73L; INT11; INTS11; RC-68; RC68
UniProt ID: (Human) Q5TA45
Entrez Gene ID: (Human) 54973
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support