Proteintech

CPT1C Monoclonal Antibody (5D11B5)

CPT1C Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CPT1C Antibody (66072-1-IG) in IHC (P)

Immunohistochemistry of paraffin-embedded human testis using 66072-1-IG (CPT1C antibody) at dilution of 1:50 (under 40x lens).

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Product Details

66072-1-IG

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Pig

Published species

Human, Mouse

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

5D11B5

Immunogen

CPT1C Fusion Protein Ag17963 (442-793 aa encoded by BC029104)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.98 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody can bind the close sequences genes.

Immunogen sequence: SFTLIVFSN GKLGLSVEHS WADCPISGHM WEFTLATECF QLGYSTDGHC KGHPDPTLPQ PQRLQWDLPD QIHSSISLAL RGAKILSENV DCHVVPFSLF GKSFIRRCHL SSDSFIQIAL QLAHFRDRGQ FCLTYESAMT RLFLEGRTET VRSCTREACN FVRAMEDKEK TDPQCLALFR VAVDKHQALL KAAMSGQGVD RHLFALYIVS RFLHLQSPFL TQVHSEQWQL STSQIPVQQM HLFDVHNYPD YVSSGGGFGP ADDHGYGVSY IFMGDGMITF HISSKKSSTK TDSHRLGQHI EDALLDVASL FQAGQHFKRR FRGSGKENSR HRCGFLSRQT GASKASMTST DF (442-793 aa encoded by BC029104)

Target Information

This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein regulates the beta-oxidation and transport of long-chain fatty acids into mitochondria, and may play a role in the regulation of feeding behavior and whole-body energy homeostasis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Cpt1c Downregulation Causes Plasma Membrane Remodelling and Anthracycline Resistance in Breast Cancer.

International journal of molecular sciences

Muley H,Valencia K,Casas J,Moreno B,Botella L,Lecanda F,Fadó R,Casals N

Wed Jan 04 00:00:00 UTC 2023

Polyphyllin I improves myocardial damage in coronary artery disease via modulating lipid metabolism and myocardial apoptosis.

Journal of biochemical and molecular toxicology

Yang Z,Yang X,An M

Thu Dec 01 00:00:00 UTC 2022

Differential regulatory roles of microRNAs during intramuscular adipogenesis in Chinese Guizhou Congjiang Xiang pigs.

Epigenetics

Tan L,Chen Z,Ruan Y,Xu H

Thu Dec 01 00:00:00 UTC 2022

MicroRNA-377-3p inhibits hepatocellular carcinoma growth and metastasis through negative regulation of CPT1C-mediated fatty acid oxidation.

Cancer & metabolism

Zhang T,Zhang Y,Liu J,Ma Y,Ye Q,Yan X,Ding L

Thu Jan 20 00:00:00 UTC 2022

MicroRNA-377-3p inhibits hepatocellular carcinoma growth and metastasis through negative regulation of CPT1C-mediated fatty acid oxidation.

Cancer & metabolism

Zhang T,Zhang Y,Liu J,Ma Y,Ye Q,Yan X,Ding L

Thu Jan 20 00:00:00 UTC 2022

MicroRNA-377-3p inhibits hepatocellular carcinoma growth and metastasis through negative regulation of CPT1C-mediated fatty acid oxidation.

Cancer & metabolism

Zhang T,Zhang Y,Liu J,Ma Y,Ye Q,Yan X,Ding L

Thu Jan 20 00:00:00 UTC 2022

MicroRNA-377-3p inhibits hepatocellular carcinoma growth and metastasis through negative regulation of CPT1C-mediated fatty acid oxidation.

Cancer & metabolism

Zhang T,Zhang Y,Liu J,Ma Y,Ye Q,Yan X,Ding L

Thu Jan 20 00:00:00 UTC 2022

Discovery of a Carbamoyl Phosphate Synthetase 1-Deficient HCC Subtype With Therapeutic Potential Through Integrative Genomic and Experimental Analysis.

Hepatology (Baltimore, Md.)

Wu T,Luo G,Lian Q,Sui C,Tang J,Zhu Y,Zheng B,Li Z,Zhang Y,Zhang Y,Bao J,Hu J,Shen S,Yang Z,Wu J,Wang K,Zhao Y,Yang S,Wang S,Qiu X,Wang W,Wu X,Wang H,Gu J,Chen L

Wed Dec 01 00:00:00 UTC 2021

Enhanced fatty acid oxidation mediated by CPT1C promotes gastric cancer progression.

Journal of gastrointestinal oncology

Chen T,Wu G,Hu H,Wu C

Sat Aug 01 00:00:00 UTC 2020

Bioinformatics

Protein Aliases: Carnitine O-palmitoyltransferase 1, brain isoform; carnitine O-palmitoyltransferase I, brain isoform; Carnitine palmitoyltransferase 1C; Carnitine palmitoyltransferase I; carnitine palmitoyltransferase I related C; CPT I-C; CPTI-B; FLJ23809; Palmitoyl thioesterase CPT1C

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Gene Aliases: CATL1; CPT1-B; CPT1C; CPT1P; CPTI-B; CPTIC; SPG73

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UniProt ID: (Human) Q8TCG5

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Entrez Gene ID: (Human) 126129

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Function(s)

carnitine O-palmitoyltransferase activity protein binding

Process(es)

fatty acid beta-oxidation carnitine metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CPT1C Monoclonal Antibody (5D11B5)

CPT1C Antibody (66072-1-IG) in IHC (P)

Product Details

66072-1-IG

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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