Proteintech

CPT2 Polyclonal Antibody

CPT2 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 11

CPT2 Antibody (26555-1-AP) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed C2C12 cells using (Product # 26555-1-AP) (CPT2 antibody) at dilution of 1:50 and CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CPT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

CPT2 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

26555-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 18 publications 18 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 4 publications 4 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CPT2 Fusion Protein Ag24897 (32-178 aa encoded by BC002445)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: GQYLQRSIV PTMHYQDSLP RLPIPKLEDT IRRYLSAQKP LLNDGQFRKT EQFCKSFENG IGKELHEQLV ALDKQNKHTS YILGPWFDMY LSARDSVVLN FNPFMAFNPD PKSEYNDQLT RATNMTVSAI RFLKTLRAGL LEPEVFHL (32-178 aa encoded by BC002445 )

Target Information

Carnitine palmitoyltransferase II precursor (CPT2) is a nuclear protein which is transported to the mitochondrial inner membrane. CPT2 together with carnitine palmitoyltransferase I oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism.

Communications biology

Landowski M,Bhute VJ,Grindel S,Haugstad Z,Gyening YK,Tytanic M,Brush RS,Moyer LJ,Nelson DW,Davis CR,Yen CE,Ikeda S,Agbaga MP,Ikeda A

Wed Jan 04 00:00:00 UTC 2023

Complementary hepatic metabolomics and proteomics reveal the adaptive mechanisms of dairy cows to the transition period.

Journal of dairy science

Zhang J,Gaowa N,Wang Y,Li H,Cao Z,Yang H,Zhang X,Li S

Wed Mar 01 00:00:00 UTC 2023

Apolipoprotein A4 Elevates Sympathetic Activity and Thermogenesis in Male Mice.

Nutrients

Kuo HN,LaRussa Z,Xu FM,West K,Consitt L,Davidson WS,Liu M,Coschigano KT,Shi H,Lo CC

Fri May 26 00:00:00 UTC 2023

Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.

Signal transduction and targeted therapy

Ma B,Ju A,Zhang S,An Q,Xu S,Liu J,Yu L,Fu Y,Luo Y

Fri Jun 16 00:00:00 UTC 2023

Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.

Signal transduction and targeted therapy

Ma B,Ju A,Zhang S,An Q,Xu S,Liu J,Yu L,Fu Y,Luo Y

Fri Jun 16 00:00:00 UTC 2023

The Role and Mechanism of CREBH Regulating SIRT3 in Metabolic Associated Fatty Liver Disease.

Life sciences

Junli Z,Shuhan W,Yajuan Z,Xiaoling D,Jiahuan L,Keshu X

Sat Oct 01 00:00:00 UTC 2022

Ketogenesis acts as an endogenous protective programme to restrain inflammatory macrophage activation during acute pancreatitis.

EBioMedicine

Zhang L,Shi J,Du D,Niu N,Liu S,Yang X,Lu P,Shen X,Shi N,Yao L,Zhang R,Hu G,Lu G,Zhu Q,Zeng T,Liu T,Xia Q,Huang W,Xue J

Fri Apr 01 00:00:00 UTC 2022

A small-molecule cocktail promotes mammalian cardiomyocyte proliferation and heart regeneration.

Cell stem cell

Du J,Zheng L,Gao P,Yang H,Yang WJ,Guo F,Liang R,Feng M,Wang Z,Zhang Z,Bai L,Bu Y,Xing S,Zheng W,Wang X,Quan L,Hu X,Wu H,Chen Z,Chen L,Wei K,Zhang Z,Zhu X,Zhang X,Tu Q,Zhao SM,Lei X,Xiong JW

Thu Apr 07 00:00:00 UTC 2022

A small-molecule cocktail promotes mammalian cardiomyocyte proliferation and heart regeneration.

Cell stem cell

Du J,Zheng L,Gao P,Yang H,Yang WJ,Guo F,Liang R,Feng M,Wang Z,Zhang Z,Bai L,Bu Y,Xing S,Zheng W,Wang X,Quan L,Hu X,Wu H,Chen Z,Chen L,Wei K,Zhang Z,Zhu X,Zhang X,Tu Q,Zhao SM,Lei X,Xiong JW

Thu Apr 07 00:00:00 UTC 2022

Adenosine-rich extract of Ganoderma lucidum: A safe and effective lipid-lowering substance.

iScience

Li H,Du Y,Ji H,Yang Y,Xu C,Li Q,Ran L,Wu C,Zhou Q,Wu S

Fri Nov 18 00:00:00 UTC 2022

Adenosine-rich extract of Ganoderma lucidum: A safe and effective lipid-lowering substance.

iScience

Li H,Du Y,Ji H,Yang Y,Xu C,Li Q,Ran L,Wu C,Zhou Q,Wu S

Fri Nov 18 00:00:00 UTC 2022

Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.

Theranostics

Li R,Li X,Zhao J,Meng F,Yao C,Bao E,Sun N,Chen X,Cheng W,Hua H,Li X,Wang B,Wang H,Pan X,You H,Yang J,Ikezoe T

Thu Mar 10 00:00:00 UTC 2022

Bifidobacterium animalis subsp. lactis A6 Enhances Fatty Acid β-Oxidation of Adipose Tissue to Ameliorate the Development of Obesity in Mice.

Nutrients

Huo Y,Zhao G,Li J,Wang R,Ren F,Li Y,Wang X

Sat Jan 29 00:00:00 UTC 2022

An integrated bioinformatic investigation of mitochondrial energy metabolism genes in colon adenocarcinoma followed by preliminary validation of CPT2 in tumor immune infiltration.

Frontiers in immunology

Cao Z,Lin J,Fu G,Niu L,Yang Z,Cai W

Mon Oct 03 00:00:00 UTC 2022

CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism.

Frontiers in oncology

Dong S,Li S,Wang X,Liang S,Zhang W,Li L,Xu Q,Shi B,Cheng Z,Zhang X,Zhong M,Zhang G,Hu S

Fri Jul 29 00:00:00 UTC 2022

CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism.

Frontiers in oncology

Dong S,Li S,Wang X,Liang S,Zhang W,Li L,Xu Q,Shi B,Cheng Z,Zhang X,Zhong M,Zhang G,Hu S

Fri Jul 29 00:00:00 UTC 2022

CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism.

Frontiers in oncology

Dong S,Li S,Wang X,Liang S,Zhang W,Li L,Xu Q,Shi B,Cheng Z,Zhang X,Zhong M,Zhang G,Hu S

Fri Jul 29 00:00:00 UTC 2022

CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism.

Frontiers in oncology

Dong S,Li S,Wang X,Liang S,Zhang W,Li L,Xu Q,Shi B,Cheng Z,Zhang X,Zhong M,Zhang G,Hu S

Fri Jul 29 00:00:00 UTC 2022

The peroxisomal transporter ABCD3 plays a major role in hepatic dicarboxylic fatty acid metabolism and lipid homeostasis.

Journal of inherited metabolic disease

Ranea-Robles P,Chen H,Stauffer B,Yu C,Bhattacharya D,Friedman SL,Puchowicz M,Houten SM

Mon Nov 01 00:00:00 UTC 2021

Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice.

Kidney360

Ranea-Robles P,Portman K,Bender A,Lee K,He JC,Mulholland DJ,Argmann C,Houten SM

Wed Sep 01 00:00:00 UTC 2021

Regulating immune memory and reversing tumor thermotolerance through a step-by-step starving-photothermal therapy.

Journal of nanobiotechnology

Luo L,Qin B,Jiang M,Xie L,Luo Z,Guo X,Zhang J,Li X,Zhu C,Du Y,Peng L,You J

Thu Sep 30 00:00:00 UTC 2021

CLN6 deficiency causes selective changes in the lysosomal protein composition.

Proteomics

Tuermer A,Mausbach S,Kaade E,Damme M,Sylvester M,Gieselmann V,Thelen M

Fri Oct 01 00:00:00 UTC 2021

Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division.

eLife

Ow JR,Caldez MJ,Zafer G,Foo JC,Li HY,Ghosh S,Wollmann H,Cazenave-Gassiot A,Ong CB,Wenk MR,Han W,Choi H,Kaldis P

Mon Dec 21 00:00:00 UTC 2020

Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division.

eLife

Ow JR,Caldez MJ,Zafer G,Foo JC,Li HY,Ghosh S,Wollmann H,Cazenave-Gassiot A,Ong CB,Wenk MR,Han W,Choi H,Kaldis P

Mon Dec 21 00:00:00 UTC 2020

Low Expression of Sirtuin 1 in the Dairy Cows with Mild Fatty Liver Alters Hepatic Lipid Metabolism.

Animals : an open access journal from MDPI

Li Y,Zou S,Ding H,Hao N,Huang Y,Tang J,Cheng J,Feng S,Li J,Wang X,Wu J

Fri Mar 27 00:00:00 UTC 2020

Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT).

PloS one

Nakano D,Kawaguchi T,Iwamoto H,Hayakawa M,Koga H,Torimura T

Thu Jul 23 00:00:00 UTC 2020

UPLC-QTOF/MS-based metabolomics analysis of plasma reveals an effect of Xue-Fu-Zhu-Yu capsules on blood-stasis syndrome in CHD rats.

Journal of ethnopharmacology

Zhao Y,Nie S,Yi M,Wu N,Wang W,Zhang Z,Yao Y,Wang D

Sun Sep 15 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: Carnitine O-palmitoyltransferase 2, mitochondrial; Carnitine palmitoyltransferase II; CPT II; OTTHUMP00000010493; testicular secretory protein Li 13

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Gene Aliases: AI323697; Cpt-2; CPT1; CPT2; CPTASE; CPTII; IIAE4

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UniProt ID: (Human) P23786, (Mouse) P52825, (Rat) P18886

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Entrez Gene ID: (Human) 1376, (Mouse) 12896, (Rat) 25413

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Function(s)

carnitine O-palmitoyltransferase activity transferase activity transferase activity, transferring acyl groups

Process(es)

lipid metabolic process fatty acid metabolic process transport fatty acid beta-oxidation metabolic process long-chain fatty acid transport carnitine shuttle

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CPT2 Polyclonal Antibody

CPT2 Antibody (26555-1-AP) in ICC/IF

Product Details

26555-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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