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Invitrogen
CRABP2 Polyclonal Antibody
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Product Details
PA5-120970
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-94 of human CRABP2 (NP_001869.1).
Conjugate
Form
Liquid
Concentration
2.61 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914542
Product Specific Information
Positive test controls include: MCF7, SW480, A-431, 22Rv1, HT-29, 293T, Mouse brain, Mouse uterus. The target is usually found in the following locations: Cytoplasm, Endoplasmic reticulum, Nucleus.
Immunogen sequence: VLGVNVMLRK IAVAAASKPA VEIKQEGDTF YIKTSTTVRT TEINFKVGEE FEEQTVDGRP CKSLVKWESE NKM
Target Information
Cellular retinoic acid binding protein (CRABP) is a low molecular weight protein with unknown function and existing in two isoforms, CRABP1 and CRABP2. The predicted amino acid sequences of human CRABP1 and CRABP2 exhibits 99.3 and 93.5% identity to mouse CRABP1 and CRABP2, respectively. The CRABP2 isoform is important in retinoic acid-mediated regulation of human skin growth and differentiation. The CRABP2 gene localized on human chromosome 1q21.3 is transcriptionally regulated by a newly synthesized regulatory protein. The protein is expressed in human adult liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cellular lipid-binding protein; cellular retinoic acid binding protein II; Cellular retinoic acid-binding protein 2; Cellular retinoic acid-binding protein II; CRABP-II; RP11-66D17.4
Gene Aliases: AI893628; Crabp-2; CRABP-II; CRABP2; CrabpII; RBP6
UniProt ID: (Human) P29373, (Mouse) P22935, (Rat) P51673
Entrez Gene ID: (Human) 1382, (Mouse) 12904, (Rat) 29563
regulation of transcription, DNA-templated
transport
signal transduction
epidermis development
embryonic forelimb morphogenesis
retinoic acid metabolic process
regulation of retinoic acid receptor signaling pathway
positive regulation of collateral sprouting
retinoic acid biosynthetic process
lipid transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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