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Invitrogen
CREB3L1 Polyclonal Antibody
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CREB3L1 Antibody (PA5-95263) in WB
Western blot analysis of CREB3L1 in Lane 1: human placenta tissue lysate (50 µg), Lane 2: HeLa whole cell lysate (40 µg), Lane 3: A549 whole cell lysate (40 µg), Lane 4: MM231 whole cell lysate (40 µg), Lane 5: COLO320 whole cell lysate (40 µg). Samples were incubated with CREB3L1 polyclonal antibody (Product # PA5-95263).
Product Details
PA5-95263
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human CREB3L1 recombinant protein (Position: M1-M204).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2807067
Product Specific Information
Human CREB3L1 shares 93.6% and 93.1% amino acid (aa) sequence identity with mouse and rat CREB3L1, respectively.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Human Placenta Tissue, HELA whole cell, A549 whole cell, MM231 whole cell, COLO320 whole cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system. May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BBF-2 homolog; cAMP responsive element binding protein 3-like 1; cAMP-responsive element-binding protein 3-like protein 1; Cyclic AMP-responsive element-binding protein 3-like protein 1; OASIS; Old astrocyte specifically-induced substance
Gene Aliases: CREB3L1; OASIS; PSEC0238
UniProt ID: (Human) Q96BA8
Entrez Gene ID: (Human) 90993
osteoblast differentiation
transcription from RNA polymerase II promoter
multicellular organism development
endoplasmic reticulum unfolded protein response
extracellular matrix constituent secretion
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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