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Abnova
CREBBP Monoclonal Antibody (2H5)
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Product Details
H00001387-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2H5
Immunogen
CREBBP (NP_004371, 951 a.a. approximately 1050 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: PVHAQPPGTP LSQAAASIDN RVPTPSSVAS AETNSQQPGP DVPVLEMKTE TQAEDTEPDP GESKGEPRSE MMEEDLQGAS QVKEETDIAE QKSEPMEVDE
Target Information
CBP for CREB-binding protein is a 265 kDa nuclear protein which probably has many of the properties expected of a CREB co-activator. It shows substantial sequence homology with p300.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CREB-binding protein; Histone lysine acetyltransferase CREBBP; Protein lactyltransferas CREBBP; Protein-lysine acetyltransferase CREBBP
Gene Aliases: CBP; CREBBP; KAT3A; RSTS
UniProt ID: (Human) Q92793
Entrez Gene ID: (Human) 1387
core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
RNA polymerase II activating transcription factor binding
RNA polymerase II transcription coactivator activity
transcriptional repressor activity, RNA polymerase II transcription factor binding
p53 binding
chromatin binding
damaged DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
histone acetyltransferase activity
signal transducer activity
protein binding
transcription factor binding
zinc ion binding
acetyltransferase activity
peptide N-acetyltransferase activity
peroxisome proliferator activated receptor binding
MRF binding
SMAD binding
negative regulation of transcription from RNA polymerase II promoter
response to hypoxia
stimulatory C-type lectin receptor signaling pathway
regulation of transcription, DNA-templated
transcription initiation from RNA polymerase II promoter
protein complex assembly
protein acetylation
signal transduction
Notch signaling pathway
cell proliferation
regulation of smoothened signaling pathway
viral process
histone acetylation
N-terminal peptidyl-lysine acetylation
positive regulation of type I interferon production
cellular response to UV
homeostatic process
embryonic digit morphogenesis
regulation of apoptotic process
cellular lipid metabolic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
positive regulation of cell adhesion molecule production
regulation of transcription from RNA polymerase II promoter in response to hypoxia
response to interleukin-1
cell-cell adhesion
regulation of cellular response to heat
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of NIK/NF-kappaB signaling
beta-catenin-TCF complex assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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