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FIGURE: 1 / 3
CRMP3 Antibody (MA5-53118) in ICC/IF
Immunocytochemistry analysis of CRMP3 in HeLa cells. Nuclei were stained blue with DAPI; CRMP3 recombinant monoclonal antibody (Product # MA5-53118) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Low. Scale bar: 20 μm.
Product Details
MA5-53118
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB1510
Immunogen
A synthesized peptide derived from human CRMP3 (15-43AA).
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3249591
Target Information
Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collapsin response mediator protein 3; CRMP-3; dihydropyrimidinase-like 4; Dihydropyrimidinase-related protein 4; DRP-4; ULIP-4; ULIP4 protein; unc-33-like phosphoprotein 4; UNC33-like phosphoprotein 4
Gene Aliases: AI173505; CRMP-3; CRMP3; DPY4; Dpys4; DPYSL4; DRP-4; ULIP4
UniProt ID: (Human) O14531, (Rat) Q62951
Entrez Gene ID: (Human) 10570, (Rat) 25417, (Mouse) 26757
Performance Guarantee
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