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Proteintech
CROT Polyclonal Antibody
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Product Details
13543-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CROT Fusion Protein Ag4486 (315-612 aa encoded by BC039004)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can bind the close sequences genes.
Immunogen sequence: SFSNGVFGC NCDHAPFDAM IMVNISYYVD EKIFQNEGRW KGSEKVRDIP LPEELIFIVD EKVLNDINQA KAQYLREASD LQIAAYAFTS FGKKLTKNKM LHPDTFIQLA LQLAYYRLHG HPGCCYETAM TRHFYHGRTE TMRSCTVEAV RWCQSMQDPS VNLRERQQKM LQAFAKHNKM MKDCSAGKGF DRHLLGLLLI AKEEGLPVPE LFTDPLFSKS GGGGNFVLST SLVGYLRVQG VVVPMVHNGY GFFYHIRDDR FVVACSAWKS CPETDAEKLV QLTFCAFHDM IQLMNSTHL (315-612 aa encoded by BC039004)
Target Information
CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4, 8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: COT; peroxisomal carnitine acyltransferase; Peroxisomal carnitine O-octanoyltransferase
Gene Aliases: 1200003H03Rik; COT; CROT
UniProt ID: (Human) Q9UKG9, (Mouse) Q9DC50, (Rat) P11466
Entrez Gene ID: (Human) 54677, (Mouse) 74114, (Rat) 83842
generation of precursor metabolites and energy
lipid metabolic process
fatty acid metabolic process
fatty acid beta-oxidation
transport
carnitine metabolic process
fatty acid transport
coenzyme A metabolic process
response to drug
medium-chain fatty acid metabolic process
response to organonitrogen compound
fatty acid beta-oxidation using acyl-CoA oxidase
medium-chain fatty acid transport
long-chain fatty acid transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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