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Immunogen sequence: HALDKYSGE HWAESVGYLE ISLRLHRLLR DSEAFCHRNC SAAPQPEPAA GLASYPELRL FGGLLRRAHC LKRCKQGLPA FRQSQPSRDV LADFQRREPY KFLQFAYFKA NNLPKAIAAA HTFLLKHPDD EMMKRNMAYY KSLPGAEDYI KDLETKSYES LFIRAVRAYN GENWRTSITD MELALPDFFK AFYECLAACE GSREIKDFKD FYLSIADHYV EVLECKIQCE ENLTPVIGGY PVEKFVATMY HYLQFAYYKL NDLKNAAPCA VSYLLFDQND KVMQQNLVYY QYHRDTWGLS DEHFQPRPEA VQFFNVTTLQ KELYDFAKEN IMDDDEGEVV EYVDDLLELE ETS (50-401 aa encoded by BC008745)
The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cartilage-associated protein; leprecan-like 3; prolyl 3-hydroxylase family member 5 (non-enzymatic)
Gene Aliases: 5730529N23Rik; CASP; CRTAP; LEPREL3; OI7; P3H5; RGD1565180
UniProt ID: (Human) O75718, (Mouse) Q9CYD3
Entrez Gene ID: (Human) 10491, (Rat) 363158, (Mouse) 56693
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