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Invitrogen
CRYZ Polyclonal Antibody
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FIGURE: 1 / 4
CRYZ Antibody (PA5-31150) in ICC/IF
zeta Crystallin antibody [N1C1] detects zeta Crystallin protein at cytoplasm by immunofluorescent analysis. Sample: HepG2 cells were fixed in ice-cold MeOH for 5 min. Green: zeta Crystallin protein stained by zeta Crystallin antibody [N1C1] (Product # PA5-31150) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 μm.
Product Details
PA5-31150
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human CRYZ. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2548624
Product Specific Information
Recommended positive controls: 293T, Jurkat, Raji, mouse brain.
Predicted reactivity: Human (99%), Mouse (81%), Rat (82%), Dog (87%), Pig (80%), Rhesus Monkey (96%), Bovine (87%), Guinea pig (85%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: crystallin, zeta (quinone reductase); nadph quinone reductase; NADPH:quinone reductase; Quinone oxidoreductase; quinone reductase; zeta crystallin; Zeta-crystallin
Gene Aliases: CRYZ; Sez9
UniProt ID: (Human) Q08257, (Mouse) P47199
Entrez Gene ID: (Human) 1429, (Mouse) 12972
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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