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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CD131 (CSF2RB) Antibodies

          Invitrogen

          CSF2RB Polyclonal Antibody

          Advanced Verification
          2 Published Figures
          1 Reference
          View all (34) CD131 (CSF2RB) antibodies

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          Datasheet
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          Datasheet
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          Cite CSF2RB Polyclonal Antibody

          • Antibody Testing Data (2)
          • Published Figures (2)
          • Advanced Verification (1)
          CSF2RB Antibody in Immunocytochemistry (ICC/IF)
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          CSF2RB Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          CSF2RB Antibody (PA5-28000) in ICC/IF

          Immunofluorescence analysis of CSF2RB was performed using 70% confluent log phase THP-1 cells treated with 10 ng of GM-CSF for 15 minutes. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with CSF2RB Rabbit Polyclonal Antibody (Product # PA5-28000) at 5 µg/mL in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibo... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          CSF2RB Antibody in Immunocytochemistry (ICC/IF)
          CSF2RB Antibody in Western Blot (WB)
          CSF2RB Antibody in Western Blot (WB)
          CSF2RB Antibody in Western Blot (WB)
          CSF2RB Antibody

          Product Details

          PA5-28000

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          5 µg/mL
          -

          Flow Cytometry (Flow)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant fragment of human IL3 Receptor beta.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          0.1M tris glycine, pH 7, with 10% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2545476

          Product Specific Information

          Recommended positive controls: K562.

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP).

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: beta common cytokine receptor; CD antigen CD131; CD131; CDw131; colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); colony-stimulating factor-2 receptor, beta, low-affinity; Cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; GM-CSF/IL-3/IL-5 receptor common beta-chain; IL-3 RB; IL-3 Receptor beta; IL3R beta; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity)

          View more View less

          Gene Aliases: CD131; CDw131; CSF2RB; IL3RB; IL5RB; SMDP5

          View more View less

          UniProt ID: (Human) P32927

          View more View less

          Entrez Gene ID: (Human) 1439

          View more View less

          Function(s)
          protein tyrosine kinase activity receptor activity interleukin-3 receptor activity interleukin-5 receptor activity Ras guanyl-nucleotide exchange factor activity protein binding
          Process(es)
          MAPK cascade signal transduction respiratory gaseous exchange peptidyl-tyrosine phosphorylation cellular response to interleukin-3 interleukin-5-mediated signaling pathway interleukin-3-mediated signaling pathway positive regulation of GTPase activity cellular protein metabolic process
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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