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Product Details
BS-1579R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human CSMD1, amino acids 3510-3565.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
CSMD1 CUB and Sushi multiple domains 1 is a protein that in humans is encoded by the CSMD1gene. It is a potential tumour suppressor, the deletion of which may result in head and neck carcinomas behaving more aggressively. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CUB and sushi domain-containing protein 1; CUB and sushi multiple domains protein 1; multiple domain complement regulator 1; protein phosphatase 1, regulatory subunit 24
Gene Aliases: B930082H09; CSMD1; KIAA1890; Mdcr1; mKIAA1890; PPP1R24; UNQ5952/PRO19863
UniProt ID: (Human) Q96PZ7, (Mouse) Q923L3
Entrez Gene ID: (Human) 64478, (Rat) 364634, (Mouse) 94109
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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