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OriGene
CST3 Monoclonal Antibody (OTI7B8), TrueMAB™
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Product Details
TA600255
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI7B8
Immunogen
Full length human recombinant protein of human CST3 produced in HEK293T cell.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with <5% trehalose
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Target Information
Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AD8; bA218C14.4 (cystatin C); cystatin 3; Cystatin-3; Cystatin-C; Cystatin3; CystatinC; epididymis secretory protein Li 2; Gamma-trace; MGC117328; Neuroendocrine basic polypeptide; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; Post-gamma-globulin; RP23-250M11.9
Gene Aliases: ARMD11; CST3; HEL-S-2
UniProt ID: (Human) P01034
Entrez Gene ID: (Human) 1471
defense response
negative regulation of peptidase activity
negative regulation of collagen catabolic process
negative regulation of extracellular matrix disassembly
negative regulation of endopeptidase activity
regulation of tissue remodeling
extracellular fibril organization
cellular protein metabolic process
negative regulation of proteolysis
negative regulation of elastin catabolic process
negative regulation of blood vessel remodeling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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