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Proteintech
CST8 Polyclonal Antibody
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Product Details
18183-1-AP
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CST8 Fusion Protein Ag12896 (1-142 aa encoded by BC069496)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPRCRWLSL ILLTIPLALV ARKDPKKNET GVLRKLKPVN ASNANVKQCL WFAMQEYNKE SEDKYVFLVV KTLQAQLQVT NLLEYLIDVE IARSDCRKPL STNEICAIQE NSKLKRKLSC SFLVGALPWN GEFTVMEKKC EDA (1-142 aa encoded by BC069496)
Target Information
The cystatin superfamily is a well-established family of cysteine protease inhibitors. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, while some also inhibit legumain family enzymes. The CRES (cystatin-related epididymal spermatogenic) protein defines a new subgroup in the family 2 cystatins of the cystatin superfamily. CRES proteins lack two of the three consensus sites necessary for the cystatin inhibition of C1 cysteine proteases. They are also preferentially expressed in postmeiotic germ cells, the proximal caput epididymidis, and anterior pituitary gonadotrophs. Therefore, CRES proteins may perform unique and tissue-specific functions in the reproductive and neuroendocrine systems. As a member of the CRES subfamily, Cystatin 8 is a 142 amino acid protein that is expressed in the proximal caput region of the epididymis, where it performs a specialized role during sperm development and maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CST 8; cystatin 8 (cystatin-related epididymal specific); Cystatin-8; Cystatin-related epididymal spermatogenic protein
Gene Aliases: CRES; CST8; CTES5
UniProt ID: (Human) O60676
Entrez Gene ID: (Human) 10047
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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