Proteintech

CTBP2 Polyclonal Antibody

FIGURE: 1 / 5

CTBP2 Antibody (10346-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with (Product # 10346-1-AP) CTBP2 antibody at dilution of 1:2,000 incubated at room temperature for 1.5 hours.

CTBP2 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

10346-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

Immunocytochemistry (ICC/IF)

Assay-dependent

View 4 publications 4 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Gerbil, Mouse, Zebrafish

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CTBP2 Fusion Protein Ag0352 (24-201 aa encoded by BC002486)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: QIMNGPLHP RPLVALLDGR DCTVEMPILK DLATVAFCDA QSTQEIHEKV LNEAVGAMMY HTITLTREDL EKFKALRVIV RIGSGYDNVD IKAAGELGIA VCNIPSAAVE ETADSTICHI LNLYRRNTWL YQALREGTRV QSVEQIREVA SGAARIRGET LGLIGFGRTG QAVAVRAKA (24-201 aa encoded by BC002486)

Target Information

This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21. 3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Hair cell identity establishes labeled lines of directional mechanosensation.

PLoS biology

Lozano-Ortega M,Valera G,Xiao Y,Faucherre A,López-Schier H

Sun Jul 01 00:00:00 UTC 2018

Hair cell identity establishes labeled lines of directional mechanosensation.

PLoS biology

Lozano-Ortega M,Valera G,Xiao Y,Faucherre A,López-Schier H

Sun Jul 01 00:00:00 UTC 2018

Specific Influences of Early Acoustic Environments on Cochlear Hair Cells in Postnatal Mice.

Neural plasticity

Chang A,Chen P,Guo S,Xu N,Pan W,Zhang H,Li C,Tang J

Tue Dec 11 00:00:00 UTC 2018

Specific Influences of Early Acoustic Environments on Cochlear Hair Cells in Postnatal Mice.

Neural plasticity

Chang A,Chen P,Guo S,Xu N,Pan W,Zhang H,Li C,Tang J

Tue Dec 11 00:00:00 UTC 2018

MicroRNA-200 family members are weakly expressed in the neurosensory epithelia of the developing zebrafish (Danio rerio) inner ear.

Genetics and molecular research : GMR

Du JT,Cao H,Zhou W,Chen KT,Jiang D,Tang HC,Wang XR,Zhang XM,Jiang HY

Mon Jun 09 00:00:00 UTC 2014

MicroRNA-200 family members are weakly expressed in the neurosensory epithelia of the developing zebrafish (Danio rerio) inner ear.

Genetics and molecular research : GMR

Du JT,Cao H,Zhou W,Chen KT,Jiang D,Tang HC,Wang XR,Zhang XM,Jiang HY

Mon Jun 09 00:00:00 UTC 2014

Tonotopic variation in the calcium dependence of neurotransmitter release and vesicle pool replenishment at mammalian auditory ribbon synapses.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Johnson SL,Forge A,Knipper M,Münkner S,Marcotti W

Wed Jul 23 00:00:00 UTC 2008

Tonotopic variation in the calcium dependence of neurotransmitter release and vesicle pool replenishment at mammalian auditory ribbon synapses.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Johnson SL,Forge A,Knipper M,Münkner S,Marcotti W

Wed Jul 23 00:00:00 UTC 2008

Bioinformatics

Protein Aliases: C-terminal-binding protein 2; CtBP2; gene trap ROSA b-geo 6; ribeye; RP11-59C5.2

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Gene Aliases: AA407280; CTBP2; D7Ertd45e; Gtrgeo6; Ribeye

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UniProt ID: (Human) P56545, (Rat) Q9EQH5, (Mouse) P56546

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Entrez Gene ID: (Human) 1488, (Rat) 81717, (Mouse) 13017

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Function(s)

chromatin binding transcription coactivator activity transcription corepressor activity protein binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor protein homodimerization activity retinoic acid receptor binding NAD binding oxidoreductase activity

Process(es)

transcription, DNA-templated positive regulation of chromatin binding negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of retinoic acid receptor signaling pathway white fat cell differentiation oxidation-reduction process negative regulation of transcription from RNA polymerase II promoter negative regulation of cell proliferation viral genome replication regulation of transcription, DNA-templated metabolic process cell differentiation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CTBP2 Polyclonal Antibody

CTBP2 Antibody (10346-1-AP) in WB

Product Details

10346-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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