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Invitrogen
CTGF Monoclonal Antibody (CL5339)
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Product Details
MA5-31420
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
CL5339
Immunogen
Recombinant protein corresponding to Human CTGF
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2787056
Product Specific Information
Immunogen sequence: LPSPDCPFPR RVKLPGKCCE EWVCDEPKDQ TVVGPALAAY RLEDTFGPDP TMIRANCLVQ TTEWSACSKT CGMG
Target Information
Connective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial cells. CTGF possesses an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain, and a cysteine knot region. CTGF plays important roles in the proliferation and differentiation of chondrocytes, induces angiogenesis, and promotes cell adhesion in fibroblasts, endothelial, and epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 2-Nov; CCN family member 2; Cellular communication network factor 2; Connective tissue growth factor; Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24); Connective tissue growth-related protein; fibroblast inducible secreated protein; fibroblast inducible secreted protein; H-CTGF; hypertrophic chondrocyte-specific gene product 24; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; Insulin-like growth factor-binding protein 8; MGC102839; Protein FISP-12
Gene Aliases: betaIG-M2; CCN2; CTGF; CTGRP; Fisp-12; Fisp12; HCS24; IGFBP8; NOV2
UniProt ID: (Human) P29279, (Mouse) P29268, (Rat) Q9R1E9
Entrez Gene ID: (Human) 1490, (Mouse) 14219, (Rat) 64032
cartilage condensation
ossification
angiogenesis
regulation of cell growth
tissue homeostasis
positive regulation of protein phosphorylation
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
cell-cell signaling
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
positive regulation of gene expression
negative regulation of gene expression
positive regulation of cell death
cell migration
cell differentiation
lung development
regulation of chondrocyte differentiation
positive regulation of collagen biosynthetic process
intracellular signal transduction
chondrocyte proliferation
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of cell differentiation
positive regulation of JNK cascade
positive regulation of cell activation
positive regulation of stress fiber assembly
cytosolic calcium ion transport
positive regulation of cardiac muscle contraction
negative regulation of cell death
connective tissue development
extracellular matrix constituent secretion
positive regulation of G0 to G1 transition
positive regulation of ERK1 and ERK2 cascade
DNA biosynthetic process
reactive oxygen species metabolic process
transcription initiation from RNA polymerase II promoter
epidermis development
response to wounding
response to glucose
organ senescence
response to estradiol
response to anoxia
response to amino acid
response to peptide hormone
response to mineralocorticoid
response to fatty acid
response to organic cyclic compound
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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