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Immunogen sequence: DANKLYCSE VLAILLQDND ENRELLGELD GIDVLLQQLS VFKRHNPSTA EEQEMMENLF DSLCSCLMLS SNRERFLKGE GLQLMNLMLR EKKISRSSAL KVLDHAMIGP EGTDNCHKFV DILGLRTIFP LFMKSPRKIK KVGTTEKEHE EHVCSILASL LRNLRGQQRT RLLNKFTEND SEKVDRLMEL HFKYLGAMQV ADKKIEGEKH DMVRRGEIID NDTEEEFYLR RLDAGLFVLQ HICYIMAEIC NANVPQIRQR VHQILNMRGS SIKIVRHIIK EYAENIGDGR SPEFRENEQK RILGLLENF (250-563 aa encoded by BC036739)
The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. Diseases associated with CTNNBL1 include Immunodeficiency 99 With Hypogammaglobulinemia And Autoimmune Cytopenias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: beta catenin-like 1; Beta-catenin-like protein 1; catenin, beta like 1; NAP; nuclear associated protein; nuclear protein NAP; Nuclear-associated protein; RP5-1118M15.1; Testis development protein NYD-SP19
Gene Aliases: 5730471K09Rik; C20orf33; CTNNBL1; dJ633O20.1; NAP; NYD-SP19; P14L; PP8304
UniProt ID: (Human) Q8WYA6, (Mouse) Q9CWL8, (Rat) Q4V8K2
Entrez Gene ID: (Human) 56259, (Mouse) 66642, (Rat) 296320
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